Pesto-Chicken Casserole

Prep: 10 min Cook: 35 min Serves: 4 Cuisine: American

A creamy, flavorful casserole combining tender chicken, pesto, and pimientos, topped with Parmesan cheese—perfect for a comforting family dinner or casual gathering.

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Ingredients

  • 2 1/2 cups chopped cooked chicken
  • 1 can cream of chicken soup
  • 1 jar diced pimientos
  • 6 cups bow tie pesto

Instructions

  1. Combine chopped cooked chicken, cream of chicken soup, diced pimientos, and bow tie pesto in a large bowl.
  2. Place the mixture into a lightly greased 1 1/2-quart baking dish.
  3. Sprinkle grated Parmesan cheese over the top.
  4. Bake at 350°F (175°C) for 35 to 40 minutes until heated through and bubbly.
  5. Serve immediately.

Tips & Substitutions

For added flavor, consider using rotisserie chicken instead of plain cooked chicken. You can substitute the cream of chicken soup with a homemade version using chicken broth and cream for a lighter option. If you're looking for a twist, try adding vegetables like spinach or zucchini. Adjust the amount of pesto based on your preference for a stronger basil flavor.

Serving Suggestions

This Pesto-Chicken Casserole pairs beautifully with a fresh green salad or roasted vegetables for a balanced meal. You might also enjoy it alongside garlic bread for a comforting dinner experience. For a more indulgent touch, serve with a sprinkle of extra Parmesan cheese or a drizzle of balsamic glaze on top.

Storage & Reheating

To store leftovers, allow the casserole to cool completely before transferring it to an airtight container. It can be kept in the refrigerator for up to 3 days. For reheating, cover with foil and warm in the oven at 350°F until heated through, or microwave individual portions for 1-2 minutes, stirring halfway.

Nutrition & Diet Analysis (per serving)

Each serving of Pesto-Chicken Casserole contains roughly 150 calories, with 6g protein, 11g carbohydrates, and 9g fat. It is a good source of protein (12% of the Daily Value). Note that it is relatively high in sodium, at 1208mg per serving (53% of the Daily Value).

150 kcal 7% DV
Protein Fat Carbs

Macronutrients

Protein 6.2g 12% DV
Total Fat 8.9g 11% DV
Carbs 11.2g 4% DV
Fiber 0g
Sugar 0.9g 2% DV

Electrolytes

Sodium 1207.8mg 53% DV
Potassium 127.5mg 3% DV
Cholesterol 19.7mg 7% DV

Vitamins & Minerals

Vitamin A 64.8mcg 7% DV
Vitamin C 0.2mg
Vitamin D 0mcg
Calcium 22.7mg 2% DV
Iron 1.7mg 9% DV
Diet fit Low-carb Under 400 cal
Contains Milk

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I use a different type of pasta instead of bow tie?

Yes, you can substitute bow tie pasta with any short pasta shape like penne or fusilli. Just make sure to adjust the cooking time according to the pasta you choose, as some may take longer to cook than others.

Is this casserole freezer-friendly?

Absolutely! You can freeze the unbaked casserole for up to 3 months. Simply cover it tightly with foil or plastic wrap. When you're ready to bake, thaw it in the refrigerator overnight and then bake as directed.

Can I add more vegetables to the recipe?

Certainly! Adding vegetables like broccoli, bell peppers, or even mushrooms can enhance the flavor and nutrition of the casserole. Just make sure to sauté any fresh vegetables first to reduce excess moisture in the dish.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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