Cream Of Mushroom Chicken

Prep: 10 min Cook: 55 min Serves: 4 Cuisine: American

Cream of Mushroom Chicken offers tender chicken breasts topped with a flavorful, spicy mushroom sauce, perfect for comforting family dinners or entertaining guests with bold flavors.

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Ingredients

  • 4 boneless chicken breasts
  • 1 tsp onion powder
  • 1 tsp garlic salt
  • 3 Tbsp cayenne pepper
  • 1 (10 oz) can cream of mushroom soup
  • Salt and pepper to taste

Instructions

  1. Preheat oven to 375°F.
  2. Place chicken breasts in a casserole dish.
  3. Bake for 35 to 40 minutes, or until chicken is tender.
  4. In a saucepan, combine cream of mushroom soup and fill the can halfway with water, then pour into the saucepan.
  5. Add cayenne pepper, onion powder, garlic salt, and pepper.
  6. Stir and bring to a boil.
  7. Pour the mushroom sauce over the cooked chicken in the casserole dish.
  8. Bake in the oven at 275°F for an additional 20 minutes.
  9. Serve the chicken on a bed of rice.

Tips & Substitutions

For a milder flavor, reduce the cayenne pepper or substitute it with paprika. If you prefer fresh ingredients, sauté fresh mushrooms with onions and garlic instead of using canned soup. To enhance the dish, consider adding fresh herbs like thyme or parsley. This recipe can also be adapted by using turkey or pork instead of chicken for variety.

Serving Suggestions

Serve the Cream Of Mushroom Chicken over a bed of fluffy rice or alongside mashed potatoes for a comforting meal. Steamed vegetables such as green beans or broccoli make great sides, adding color and nutrition. This dish pairs beautifully with a fresh garden salad for a balanced dinner.

Storage & Reheating

Leftovers can be stored in an airtight container in the refrigerator for up to 3 days. To reheat, place the chicken and sauce in an oven-safe dish and cover with foil, heating at 350°F until warmed through, about 20-25 minutes. Alternatively, you can microwave individual servings for quick reheating.

Nutrition & Diet Analysis (per serving)

Each serving of Cream Of Mushroom Chicken contains roughly 372 calories, with 16g protein, 66g carbohydrates, and 18g fat. It is an excellent source of vitamin A (231% of the Daily Value), dietary fiber (103% of the Daily Value), and vitamin C (88% of the Daily Value), and a good source of calcium. Note that it is relatively high in sodium, at 678mg per serving (29% of the Daily Value).

372 kcal 19% DV
Protein Fat Carbs

Macronutrients

Protein 15.8g 32% DV
Total Fat 17.7g 23% DV
Carbs 66g 24% DV
Fiber 28.9g 100% DV
Sugar 11.2g 22% DV

Electrolytes

Sodium 677.7mg 29% DV
Potassium 2179.4mg 46% DV
Cholesterol 7.7mg 3% DV

Vitamins & Minerals

Vitamin A 2081.4mcg 100% DV
Vitamin C 79mg 88% DV
Vitamin D 0mcg
Calcium 193.4mg 15% DV
Iron 8.3mg 46% DV
Diet fit High-fiber Under 400 cal
Contains Milk

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I use frozen chicken breasts for this recipe?

Yes, you can use frozen chicken breasts, but make sure to thaw them completely before baking. Cooking from frozen may increase the cooking time significantly, so ensure the internal temperature reaches 165°F for food safety.

What can I substitute for cream of mushroom soup?

If you don't have cream of mushroom soup, you can create a homemade version using heavy cream, sautéed mushrooms, and a bit of chicken broth. Blend them until smooth and season with salt and pepper for a similar consistency and flavor.

Can this dish be made in a slow cooker?

Absolutely! For a slow cooker version, combine the chicken breasts, cream of mushroom soup, and seasonings in the Crock-Pot. Cook on low for 4-6 hours or until the chicken is tender. This method allows the flavors to meld beautifully.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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