Cheese Manicotti With Meat Sauce

Prep: 20 min Cook: 30 min Serves: 6 Cuisine: Italian

Creamy cheese manicotti filled with a rich blend of cheeses, complemented by savory meat sauce, perfect for family dinners or special occasions craving Italian comfort food.

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Ingredients

  • 1 1/2 c. shredded Mozzarella cheese
  • 1 1/2 c. shredded Cheddar cheese
  • 1 c. Ricotta cheese
  • 1 c. cottage cheese
  • 1/4 c. Romano cheese
  • 2 eggs
  • 1/2 tsp. salt

Instructions

  1. Cook the manicotti according to the package instructions.
  2. Mix all cheeses and eggs together with salt to prepare the filling.
  3. Fill each cooked manicotti with the cheese mixture.
  4. Prepare a meat sauce and pour over the filled manicotti.
  5. Bake until bubbly and cheese is golden.

Tips & Substitutions

For a creamier filling, consider adding a splash of heavy cream or a dollop of sour cream. If you're short on time, store-bought meat sauce can be a great substitute for homemade. You can also swap in ricotta for mascarpone for a richer taste. For a vegetarian option, try using a lentil-based sauce instead of meat.

Serving Suggestions

Serve the cheese manicotti with a side of garlic bread or Italian Herb Bread for a complete meal. A crisp green salad with a light vinaigrette pairs well to balance the richness of the dish. For a hearty touch, consider including Grandma Naclerio'S Meatballs on the side. This dish also works beautifully as a make-ahead option for gatherings.

Storage & Reheating

Leftovers can be stored in an airtight container in the refrigerator for up to three days. To reheat, place the manicotti in a baking dish, cover with foil, and warm in a 350°F oven until heated through, about 20-25 minutes. You can also microwave individual portions, but be aware that they may lose some texture.

Nutrition & Diet Analysis (per serving)

Each serving of Cheese Manicotti With Meat Sauce contains roughly 576 calories, with 32g protein, 40g carbohydrates, and 33g fat. It is an excellent source of calcium (73% of the Daily Value), protein (63% of the Daily Value), and vitamin A (37% of the Daily Value). Note that it is relatively high in sodium, at 1128mg per serving (49% of the Daily Value).

576 kcal 29% DV
Protein Fat Carbs

Macronutrients

Protein 31.7g 63% DV
Total Fat 32.6g 42% DV
Carbs 39.7g 14% DV
Fiber 0g
Sugar 1.7g 3% DV

Electrolytes

Sodium 1127.8mg 49% DV
Potassium 414.7mg 9% DV
Cholesterol 201.5mg 67% DV

Vitamins & Minerals

Vitamin A 329.5mcg 37% DV
Vitamin C 0.2mg
Vitamin D 0.6mcg 3% DV
Calcium 942.5mg 73% DV
Iron 1.1mg 6% DV
Diet fit High-protein
Contains Milk Egg

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I make the cheese filling ahead of time?

Yes, you can prepare the cheese filling a day in advance. Keep it stored in the refrigerator in an airtight container. Just give it a good stir before using it to fill the manicotti shells.

What kind of meat sauce works best?

A traditional meat sauce with ground beef, sausage, or turkey enhances the flavors of the manicotti. Tom'S Plain Tomato Sauce works well as a base if you prefer to keep it simple. You can also add vegetables like bell peppers or mushrooms for added nutrition.

Can I freeze the manicotti?

Yes, you can freeze assembled manicotti before baking. Wrap them tightly in plastic wrap and foil. They can be frozen for up to three months. When ready to bake, thaw in the refrigerator overnight before cooking as directed.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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