Mexican Picante Chicken Casserole

Prep: 30 min Cook: 30 min Serves: 6 Cuisine: Mexican

A flavorful Mexican-inspired chicken casserole featuring tender chicken, crispy tortilla chips, melty cheeses, and a spicy picante sauce, perfect for satisfying family dinners or casual gatherings.

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Ingredients

  • 1 large chicken
  • 1 package tortilla chips
  • 1 small package Velveeta shredded cheese
  • 1 (16 oz.) package Mozzarella cheese
  • 1/2 cup picante sauce

Instructions

  1. Boil and season the chicken as desired.
  2. Save the broth from boiling the chicken.
  3. Remove the chicken from the bone and shred it.
  4. Layer tortilla chips, shredded chicken, and cheeses in a casserole dish.
  5. Combine the picante sauce with the chicken broth and pour halfway up the side of the casserole dish.
  6. Bake at 350°F until the cheeses turn brown.

Tips & Substitutions

To enhance flavor, consider seasoning the chicken with cumin and chili powder while boiling. If you prefer a lighter option, substitute the Velveeta with a reduced-fat cheese or use a mix of cheddar and Monterey Jack. For added texture, try incorporating black beans or corn layers. This dish can also be adapted into Chicken Sinora by adding green chilies for a spicy kick.

Serving Suggestions

This Mexican Picante Chicken Casserole is delicious served with a side of fresh guacamole and sour cream. A simple green salad or Mexican rice pairs well to balance the richness of the cheese. For an extra crunch, serve with tortilla melts or alongside chili con queso soup from Neiman-Marcus for a hearty meal.

Storage & Reheating

Store leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, place the casserole in a preheated oven at 350°F for about 20-25 minutes until warmed through. Alternatively, you can microwave individual portions, covered, for 2-3 minutes, stirring halfway through for even heating.

Nutrition & Diet Analysis (per serving)

Each serving of Mexican Picante Chicken Casserole contains roughly 207 calories, with 13g protein, 17g carbohydrates, and 9g fat. It is an excellent source of protein (26% of the Daily Value) and calcium (24% of the Daily Value), and a good source of vitamin A. Note that it is relatively high in sodium, at 546mg per serving (24% of the Daily Value).

207 kcal 10% DV
Protein Fat Carbs

Macronutrients

Protein 13.2g 26% DV
Total Fat 9.1g 12% DV
Carbs 16.7g 6% DV
Fiber 0.9g 3% DV
Sugar 1.6g 3% DV

Electrolytes

Sodium 545.9mg 24% DV
Potassium 168.2mg 4% DV
Cholesterol 30mg 10% DV

Vitamins & Minerals

Vitamin A 88.1mcg 10% DV
Vitamin C 0mg
Vitamin D 0.1mcg 1% DV
Calcium 316.1mg 24% DV
Iron 0.4mg 2% DV
Diet fit Low-carb Under 400 cal
Contains Milk

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

What can I substitute for tortilla chips in the casserole?

If you want a healthier alternative, consider using baked tortilla chips or even crushed tortilla wraps. For a gluten-free option, look for corn chips or gluten-free tortillas to layer in your dish.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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