One-Dish Chicken Bake

Prep: 10 min Cook: 35 min Serves: 4 Cuisine: American

A comforting one-dish chicken bake featuring tender chicken breasts topped with savory stuffing, creamy mushroom soup, and a rich sour cream sauce. This easy-to-make casserole offers hearty flavors perfect for busy weeknights or family dinners, combining classic ingredients in a satisfying, crowd-pleasing dish.

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Ingredients

  • 6 oz. package of Stove Top stuffing mix
  • 4 boneless skinless chicken breast halves (about 1 1/4 lb.)
  • 1 can condensed cream of mushroom soup
  • 1/3 cup Breakstone sour cream or milk

Instructions

  1. Preheat oven to 375°F.
  2. Mix the contents of the stuffing mix pouch with 1 2/3 cups water; set aside.
  3. Place chicken breasts in a 13 x 9-inch baking dish or a 2-quart casserole dish.
  4. Mix the condensed cream of mushroom soup with sour cream or milk.
  5. Pour the soup mixture over the chicken.
  6. Spoon the prepared stuffing evenly over the chicken.
  7. Bake for 35 minutes or until the chicken is cooked through.

Tips & Substitutions

For optimal flavor, consider adding some garlic powder or onion powder to the chicken before baking. If you're out of sour cream, plain Greek yogurt can be a great substitute for a creamy texture. You can also use any leftover stuffing mix from previous meals or try a different flavor for variety. This dish is a comforting option, similar to Chicken-Pepper Pot.

Serving Suggestions

This One-Dish Chicken Bake is delicious served with a side of steamed green beans or a fresh garden salad. For a heartier meal, consider pairing it with mashed potatoes or a side of Au Gratin Potato Casserole(Texas-Style). Drizzling a light gravy over the top can also enhance the flavors.

Storage & Reheating

Store any leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, place the chicken bake in an oven-safe dish, cover with foil, and warm it in a 350°F oven until heated through. You can also microwave individual portions for faster reheating, but the oven method helps maintain texture.

Nutrition & Diet Analysis (per serving)

Each serving of One-Dish Chicken Bake contains roughly 179 calories, with 6g protein, 25g carbohydrates, and 6g fat. It is a good source of protein (11% of the Daily Value) and iron (10% of the Daily Value). Note that it is relatively high in sodium, at 992mg per serving (43% of the Daily Value).

179 kcal 9% DV
Protein Fat Carbs

Macronutrients

Protein 5.6g 11% DV
Total Fat 6.4g 8% DV
Carbs 24.8g 9% DV
Fiber 0.4g 1% DV
Sugar 2.2g 4% DV

Electrolytes

Sodium 991.8mg 43% DV
Potassium 143.9mg 3% DV
Cholesterol 12.4mg 4% DV

Vitamins & Minerals

Vitamin A 74mcg 8% DV
Vitamin C 0.6mg 1% DV
Calcium 76.6mg 6% DV
Iron 1.7mg 10% DV
Diet fit Under 400 cal
Contains Milk

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I use frozen chicken breasts for this recipe?

Yes, you can use frozen chicken breasts, but be sure to adjust the cooking time. They may require an additional 10-15 minutes in the oven to cook thoroughly. Always check the internal temperature to ensure it reaches 165°F for safety.

What can I substitute for cream of mushroom soup?

If you don't have cream of mushroom soup, you can use cream of chicken soup or even a homemade white sauce with sautéed mushrooms for a fresher taste. This will keep the dish creamy while adding a unique flavor twist.

Can I make this dish ahead of time?

Absolutely! You can assemble the dish up to a day in advance, cover it tightly, and refrigerate. Just be sure to add a few extra minutes to the baking time if baking directly from the fridge.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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