24 Hour Brisket

Prep: 1440 min Cook: 1440 min Serves: 8 Cuisine: American

Slow-cooked brisket infused with smoky, tangy flavors, perfect for gatherings or hearty family dinners, offering tender meat with a rich, saucy glaze.

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Ingredients

  • 5 lb. boneless beef brisket, well trimmed
  • 1 cup strong coffee
  • 10 oz. bottle Coca-Cola
  • 3 Tbsp. brown sugar
  • 2 Tbsp. prepared mustard
  • 1/4 tsp. Tabasco sauce
  • 2 cups catsup
  • 1/4 cup Worcestershire sauce
  • 2 Tbsp. Liquid Smoke

Instructions

  1. Twenty-four hours ahead, place the brisket (fat side up) in a heavy foil or covered baking dish.
  2. Pour coffee over the brisket; seal or cover and bake in a preheated 200°F oven for 24 hours.
  3. When it has baked 24 hours, remove from oven; pour off all the liquid and discard it.
  4. Place the meat on a cutting board and trim off all the excess fat.
  5. Slice the brisket into strips.
  6. Put the sliced brisket back into the pan.
  7. In a mixing bowl, combine the remaining ingredients and mix well to make the sauce.
  8. Pour the sauce over the brisket in the pan.
  9. Bake at 200°F for at least 1 more hour.

Tips & Substitutions

For a deeper flavor, consider marinating the brisket in the coffee and Coca-Cola mixture overnight before cooking. If you don't have Liquid Smoke, smoked paprika can be a good substitute. Make sure to trim the brisket well to avoid excess fat. This recipe can also be adapted for a slow cooker; check out our Crock-Pot Barbecued Beef Stew for a similar method.

Serving Suggestions

Serve the brisket sliced thin with the sauce poured over the top. It pairs beautifully with coleslaw, cornbread, or mashed potatoes for a hearty meal. For a unique twist, consider serving it in sandwiches or tacos. This dish also complements other hearty American recipes like Texas Barbecued Beef for a barbecue feast.

Storage & Reheating

Store any leftover brisket in an airtight container in the refrigerator for up to 4 days. To reheat, gently warm the brisket in the oven at 200°F, covered with foil, to maintain moisture. Alternatively, you can reheat it in a microwave, but be careful not to overcook it, as this can make the meat tough.

Nutrition & Diet Analysis (per serving)

Each serving of 24 Hour Brisket contains roughly 198 calories, with 14g protein, 8g carbohydrates, and 13g fat. It is an excellent source of protein (28% of the Daily Value), and a good source of vitamin A and iron.

198 kcal 10% DV
Protein Fat Carbs

Macronutrients

Protein 13.8g 28% DV
Total Fat 12.6g 16% DV
Carbs 8.2g 3% DV
Fiber 0.3g 1% DV
Sugar 7.3g 15% DV

Electrolytes

Sodium 334.1mg 15% DV
Potassium 343.1mg 7% DV
Cholesterol 61.1mg 20% DV

Vitamins & Minerals

Vitamin A 109.3mcg 12% DV
Vitamin C 4mg 4% DV
Vitamin D 0.5mcg 2% DV
Calcium 61.2mg 5% DV
Iron 1.9mg 10% DV
Diet fit Keto-friendly Under 400 cal

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I use a different cut of beef for this recipe?

Yes, while brisket is ideal for its flavor and tenderness after slow cooking, you can substitute with a chuck roast or even a round roast. Just be aware that cooking times may vary, and you may need to adjust seasoning to suit the different cut.

How can I make this recipe gluten-free?

To make this brisket gluten-free, simply substitute the Worcestershire sauce with a gluten-free version, which is readily available in most stores. Ensure that your catsup is also gluten-free, as some brands may contain wheat. The rest of the ingredients are naturally gluten-free.

What should I do if my brisket is tough after cooking?

If your brisket turns out tough, it may need more time in the oven. The low and slow cooking method helps break down connective tissues, so try covering it and baking for an additional hour or two. Slicing it against the grain can also help improve tenderness when serving.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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