Artichoke Spinach Cheese Casserole

Prep: 15 min Cuisine: American

A creamy, cheesy casserole combining tender artichoke hearts and spinach, perfect as a warm side dish or appetizer for gatherings and family dinners.

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Ingredients

  • 1 (8 1/2 oz.) jar marinated artichoke hearts, drained
  • 2 (10 oz.) packages frozen chopped spinach, thawed
  • 1 (8 oz.) package cream cheese
  • 2 Tbsp. softened butter or margarine
  • 4 Tbsp. milk

Instructions

  1. Put artichoke hearts in a medium casserole dish.
  2. Squeeze the thawed spinach dry and arrange evenly over the artichoke hearts.
  3. Beat the cream cheese and softened butter until smooth.
  4. Gradually add the milk to the cream cheese mixture, mixing well.
  5. Spread the cream cheese mixture over the spinach and artichokes; add pepper to taste.
  6. Sprinkle with Parmesan cheese on top.
  7. Cover and refrigerate for 24 hours before serving.

Tips & Substitutions

For a creamier texture, consider adding a bit more milk or using sour cream instead of some of the cream cheese. You can also substitute fresh spinach for frozen, just be sure to wilt and chop it beforehand. If you want a hint of zest, a squeeze of lemon juice can brighten up the flavors. Pair this dish with Oven Dirty Rice for a complete meal.

Serving Suggestions

This Artichoke Spinach Cheese Casserole makes a great appetizer or side dish. Serve it warm with toasted baguette slices, or pair it with a fresh Spinach-Beet Salad for a light meal. For a heartier option, it goes well alongside grilled chicken or fish. A glass of white wine complements the flavors beautifully.

Storage & Reheating

Store any leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, preheat your oven to 350°F (175°C) and cover the casserole with foil to prevent drying out. Heat for about 20-25 minutes until warmed through. You can also microwave individual portions, covered, in short intervals until hot.

Nutrition & Diet Analysis (per serving)

Each serving of Artichoke Spinach Cheese Casserole contains roughly 451 calories, with 13g protein, 29g carbohydrates, and 34g fat. It is an excellent source of protein (26% of the Daily Value), iron (24% of the Daily Value), and dietary fiber (23% of the Daily Value), and a good source of potassium. It also contributes 6g of dietary fiber toward your daily target.

451 kcal 23% DV
Protein Fat Carbs

Macronutrients

Protein 13.1g 26% DV
Total Fat 33.6g 43% DV
Carbs 29.4g 11% DV
Fiber 6.4g 23% DV
Sugar 5.8g 12% DV

Electrolytes

Sodium 448.6mg 20% DV
Potassium 504.8mg 11% DV
Cholesterol 99.5mg 33% DV

Vitamins & Minerals

Vitamin A 198.1mcg 22% DV
Vitamin C 1.2mg 1% DV
Vitamin D 0.4mcg 2% DV
Calcium 301.8mg 23% DV
Iron 4.3mg 24% DV
Diet fit High-fiber
Contains Milk

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I use fresh artichokes instead of marinated ones?

Yes, you can use fresh artichokes if you prefer. Just cook and marinate them yourself with olive oil, lemon juice, and seasonings to replicate the flavor of the jarred artichokes. It will add a fresh twist to the casserole.

Is there a way to make this dish dairy-free?

Absolutely! You can substitute the cream cheese with a dairy-free alternative like cashew cream or a vegan cream cheese. Use plant-based milk instead of regular milk and ensure your butter or margarine is dairy-free as well.

Can I prepare this casserole in advance?

Yes, this casserole is perfect for making ahead of time. Prepare it as instructed, cover it tightly, and refrigerate for up to 24 hours before baking. It allows the flavors to meld beautifully and makes it an excellent choice for entertaining.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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