Broccoli-Mushroom-Bisquick Bake

Prep: 10 min Cook: 30 min Serves: 6 Cuisine: American

A hearty baked casserole combining broccoli, mushrooms, ham, and cheesy soups, topped with a Bisquick crust—perfect for a comforting family dinner or potluck dish.

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Ingredients

  • 1 pkg frozen broccoli cuts, rinsed and drained
  • 1 can cream of mushroom soup
  • 1 can condensed Cheddar cheese soup
  • 1 cup milk
  • 3 cups cooked ham, chicken, turkey or beef, cut up
  • 1/2 teaspoon onion powder
  • 2 cups Bisquick

Instructions

  1. Mix broccoli, cream of mushroom soup, cream of Cheddar cheese soup, 1 cup of milk, cooked ham, and onion powder in an ungreased 13 x 9-inch baking dish.
  2. Mix Bisquick and 1 1/2 cups of milk until smooth; pour evenly over the soup mixture.
  3. Bake at 400°F for 30 minutes. Let stand for 5 minutes before serving.

Tips & Substitutions

For a creamier texture, consider adding a dollop of sour cream or Greek yogurt to the soup mixture. You can substitute the frozen broccoli with fresh broccoli, just blanch it first. If you're short on Bisquick, a homemade biscuit mix can work in a pinch. This dish can also be customized with leftover vegetables or different meats such as in the Chicken-In-A-Biscuit.

Serving Suggestions

This Broccoli-Mushroom-Bisquick Bake makes a hearty main dish perfect for lunch or dinner. Serve it alongside a fresh green salad or roasted vegetables for a balanced meal. It also pairs well with crusty bread or a light soup. For variations, try serving it with a side of baked chicken or any of your favorite American recipes.

Storage & Reheating

Store leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, place individual portions in the microwave for 1-2 minutes or until heated through. Alternatively, reheat in the oven at 350°F for about 15-20 minutes until warmed. Avoid reheating multiple times to maintain quality.

Nutrition & Diet Analysis (per serving)

Each serving of Broccoli-Mushroom-Bisquick Bake contains roughly 768 calories, with 17g protein, 143g carbohydrates, and 17g fat. It is an excellent source of calcium (59% of the Daily Value), iron (55% of the Daily Value), and dietary fiber (38% of the Daily Value), and a good source of vitamin D. Note that it is relatively high in sodium, at 548mg per serving (24% of the Daily Value).

768 kcal 38% DV
Protein Fat Carbs

Macronutrients

Protein 17.1g 34% DV
Total Fat 16.5g 21% DV
Carbs 142.5g 52% DV
Fiber 10.8g 38% DV
Sugar 60.8g 100% DV

Electrolytes

Sodium 548mg 24% DV
Potassium 1024.8mg 22% DV
Cholesterol 13mg 4% DV

Vitamins & Minerals

Vitamin A 230.5mcg 26% DV
Vitamin C 34.4mg 38% DV
Vitamin D 2.1mcg 10% DV
Calcium 761.8mg 59% DV
Iron 10mg 55% DV
Diet fit High-fiber Low-fat
Contains Milk

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I use fresh broccoli instead of frozen?

Yes, fresh broccoli can be used instead of frozen. Just make sure to blanch it in boiling water for a couple of minutes before adding it to the dish. This will help soften the broccoli and enhance its flavor in the bake.

Is it possible to make this dish vegetarian?

Absolutely! You can replace the meat with additional vegetables like bell peppers or mushrooms, and use a vegetable-based cream soup. This will keep the flavors rich while making it suitable for vegetarians.

How can I make this dish spicier?

To add some heat, consider mixing in diced jalapeños or a splash of hot sauce to the soup mixture. You could also sprinkle some crushed red pepper flakes on top before baking to elevate the spice level in this comforting dish.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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