Cheeseburger Casserole(Yields 6 Servings)

Prep: 10 min Cook: 20 min Serves: 6 Cuisine: American

A hearty, cheesy casserole combining seasoned ground beef, savory tomato sauce, and melty American cheese, topped with fluffy refrigerator biscuits. Perfect for family dinners, it offers comfort food flavors with minimal prep, baked to golden perfection. An easy, crowd-pleasing dish for weeknights or casual gatherings.

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Ingredients

  • American cheese
  • lemon pepper
  • onion
  • refrigerator biscuits
  • catsup
  • tomato sauce
  • ground beef
  • salt

Instructions

  1. Combine ground beef and chopped onion in a skillet; cook until the beef is lightly browned.
  2. Drain excess fat; add salt and lemon pepper seasoning.
  3. Stir in catsup and tomato sauce; heat thoroughly.
  4. Pour the beef mixture into an 8-inch square pan or 1 1/2-quart casserole dish.
  5. Sprinkle slices of American cheese over the beef mixture.
  6. Top with refrigerator biscuits.
  7. Bake in a preheated oven at 425°F (220°C) for 20 to 25 minutes or until the biscuits are golden brown.

Tips & Substitutions

For an extra layer of flavor, consider adding garlic powder or Worcestershire sauce to the beef mixture. If American cheese isn't available, cheddar or mozzarella can be great substitutes. To save time, you can use pre-cooked ground beef. Also, feel free to add vegetables like bell peppers or mushrooms to enhance the dish, similar to what you might find in a Potluck Casserole.

Serving Suggestions

This Cheeseburger Casserole pairs wonderfully with a simple side salad or coleslaw for a refreshing contrast. You can also serve it with pickles or a dollop of sour cream on top for added creaminess. For a heartier meal, consider serving it alongside baked beans, reminiscent of classic American recipes.

Storage & Reheating

Leftovers can be stored in an airtight container in the refrigerator for up to 3 days. To reheat, place in the microwave for 2-3 minutes or until heated through, or re-bake in the oven at 350°F (175°C) for about 15-20 minutes, covered with foil to prevent drying out.

Nutrition & Diet Analysis (per serving)

Each serving of Cheeseburger Casserole(Yields 6 Servings) contains roughly 8 calories, with 1g protein, 1g carbohydrates, and 0g fat.

8 kcal
Protein Fat Carbs

Macronutrients

Protein 0.6g 1% DV
Total Fat 0.4g
Carbs 0.6g
Fiber 0g
Sugar 0.3g 1% DV

Electrolytes

Sodium 358.8mg 16% DV
Potassium 9.7mg
Cholesterol 1.3mg

Vitamins & Minerals

Vitamin A 0.9mcg
Vitamin C 0.1mg
Calcium 6.6mg 1% DV
Iron 0mg
Diet fit Keto-friendly Under 400 cal
Contains Milk

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I make this casserole ahead of time?

Yes, you can prepare the beef mixture and assemble the casserole a day in advance. Just cover it and store it in the refrigerator. When ready to bake, add the biscuits on top and increase the baking time slightly as it will be cold from the fridge.

What can I substitute for refrigerator biscuits?

If you don't have refrigerator biscuits, you can use homemade biscuit dough or even crescent roll dough as a substitute. Both will provide a delicious, flaky topping that complements the beef base nicely.

Can I freeze this casserole?

Yes, this casserole can be frozen before or after baking. If freezing before baking, wrap it tightly in plastic wrap and foil. To bake, thaw in the refrigerator overnight and then bake as directed. If freezing after baking, reheat from frozen; it may take longer to warm through.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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