Chicken And Mushroom Casserole

Prep: 15 min Cook: 60 min Serves: 4 Cuisine: American

A comforting chicken and mushroom casserole featuring tender chicken breasts in a creamy mushroom sauce, perfect for cozy family dinners. The rich flavors of mushroom soup and sour cream create a luscious dish that pairs beautifully with rice or pasta, making it a satisfying and versatile meal.

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Ingredients

  • 2 Tbsp. butter
  • 4 to 6 skinless chicken breasts
  • 1 small can cream of mushroom soup (undiluted)
  • 8 oz. sour cream
  • 4 oz. can sliced mushrooms, drained
  • cooked rice or pasta

Instructions

  1. Melt butter in a heavy covered skillet.
  2. Brown the chicken breasts on both sides.
  3. Remove the chicken and drain excess fat.
  4. Stir in the cream of mushroom soup and loosen pan drippings.
  5. Add sour cream, stirring until well mixed, then return the chicken to the skillet.
  6. Cover and simmer over very low heat until the chicken is tender, about 50 to 60 minutes.
  7. Stir in the sliced mushrooms during the last couple of minutes of cooking.
  8. Serve the casserole over cooked rice or pasta.

Tips & Substitutions

For a creamier texture, you can substitute Greek yogurt for sour cream. If you want to add more flavor, consider incorporating garlic or onions while browning the chicken. This dish can also be made with leftovers from other chicken recipes, such as Patti's Chicken, for a quick meal. Adjust cooking time if using thicker chicken breasts or frozen chicken.

Serving Suggestions

Serve the casserole over a bed of cooked rice or pasta for a hearty meal. A fresh salad or steamed vegetables would pair nicely as a side, balancing the richness of the dish. For a comforting twist, consider serving it with a side of warm bread or biscuits, which can soak up the delicious sauce.

Storage & Reheating

Store leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, place the casserole in a preheated oven at 350°F (175°C) for about 20-30 minutes or until heated through. You can also microwave portions on medium power, stirring occasionally to ensure even heating.

Nutrition & Diet Analysis (per serving)

Each serving of Chicken And Mushroom Casserole contains roughly 315 calories, with 26g protein, 26g carbohydrates, and 12g fat. It is an excellent source of vitamin D (76% of the Daily Value) and protein (52% of the Daily Value), and a good source of iron and potassium. At about 315 calories per serving, it is a lighter, protein-rich choice.

315 kcal 16% DV
Protein Fat Carbs

Macronutrients

Protein 26.1g 52% DV
Total Fat 11.9g 15% DV
Carbs 25.7g 9% DV
Fiber 1g 3% DV
Sugar 1.8g 4% DV

Electrolytes

Sodium 332mg 14% DV
Potassium 463.6mg 10% DV
Cholesterol 68.7mg 23% DV

Vitamins & Minerals

Vitamin A 32.1mcg 4% DV
Vitamin C 1.3mg 1% DV
Vitamin D 15.3mcg 76% DV
Calcium 31.9mg 2% DV
Iron 1.9mg 10% DV
Diet fit High-protein Under 400 cal
Contains Milk Wheat/Gluten

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I use frozen chicken breasts for this recipe?

Yes, you can use frozen chicken breasts, but be sure to thaw them before cooking. If using frozen, it may take longer to brown, and the cooking time will need to be adjusted to ensure the chicken is fully cooked through.

Can I make this casserole ahead of time?

Absolutely! You can prepare the casserole up to the point of cooking, cover it, and store it in the refrigerator overnight. When ready to cook, simply place it in the oven and adjust the cooking time as needed for a cold casserole.

What can I use instead of cream of mushroom soup?

If you want to avoid canned soups, you can make a homemade version using sautéed mushrooms, flour, broth, and cream. This will provide a fresh flavor and a similar consistency, enhancing the overall taste of your casserole.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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