Chicken Parmesan Casserole

Prep: 20 min Cook: 30 min Serves: 4 Cuisine: Italian

A comforting baked chicken and pasta casserole layered with flavorful cheeses and rich tomato sauce, perfect for family dinners and cheese lovers alike.

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Ingredients

  • 2 boneless chicken breasts
  • 16 oz. jar spaghetti sauce
  • 8 oz. grated Mozzarella cheese
  • 8 oz. grated Cooper sharp cheese
  • 8 oz. La Pecorina cheese
  • 1 lb. elbow macaroni

Instructions

  1. Preheat oven to 350°F.
  2. Boil chicken breasts until cooked through.
  3. Cube the cooked chicken into bite-sized pieces.
  4. In a separate pot, heat up spaghetti sauce and add the chicken cubes.
  5. Simmer the sauce and chicken together for 15 minutes.
  6. Cook the elbow macaroni until al dente.
  7. Mix the grated Mozzarella, Cooper sharp, and La Pecorina cheeses together in a bowl.
  8. Stir half of the cheese mixture into the chicken and sauce mixture.
  9. Spread the cooked macaroni in a baking dish and pour the chicken and sauce mixture over it.
  10. Sprinkle the remaining cheese mixture evenly on top.
  11. Bake in the oven for 15 minutes or until the cheese is browned and crispy.
  12. Remove from the oven and let stand for 5 to 10 minutes before serving.

Tips & Substitutions

For a lighter version, you can substitute the pasta with zucchini noodles or use whole wheat elbow macaroni. You can also swap the cheeses for lower-fat options or use a combination of your favorites. If you're short on time, pre-cooked rotisserie chicken works well. Ensure not to overcook the pasta; it should be al dente as it will continue cooking in the oven.

Serving Suggestions

Serve the Chicken Parmesan Casserole with a side salad or garlic bread for a complete meal. It pairs beautifully with Vodka Sauce for a tangy twist. Consider topping with fresh basil or parsley for added flavor. This dish is perfect for family gatherings or meal prep, as it provides generous portions and is comforting on cold evenings.

Storage & Reheating

To store leftovers, allow the casserole to cool completely, then transfer it to an airtight container. It can be refrigerated for up to three days. For reheating, place individual portions in the microwave or reheat the entire dish in the oven at 350°F until warmed through, ensuring the cheese melts again for the best texture.

Nutrition & Diet Analysis (per serving)

Each serving of Chicken Parmesan Casserole contains roughly 594 calories, with 46g protein, 27g carbohydrates, and 33g fat. It is an excellent source of protein (93% of the Daily Value), calcium (69% of the Daily Value), and vitamin A (33% of the Daily Value), and a good source of potassium and iron. Note that it is relatively high in sodium, at 1249mg per serving (54% of the Daily Value).

594 kcal 30% DV
Protein Fat Carbs

Macronutrients

Protein 46.4g 93% DV
Total Fat 33.2g 43% DV
Carbs 26.7g 10% DV
Fiber 1.8g 6% DV
Sugar 5.4g 11% DV

Electrolytes

Sodium 1249.3mg 54% DV
Potassium 554.5mg 12% DV
Cholesterol 120.2mg 40% DV

Vitamins & Minerals

Vitamin A 300.1mcg 33% DV
Vitamin C 0.8mg 1% DV
Vitamin D 0.7mcg 3% DV
Calcium 899.5mg 69% DV
Iron 1.8mg 10% DV
Diet fit High-protein
Contains Milk

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I use other types of cheese for this casserole?

Absolutely! You can substitute any melty cheese you enjoy, such as provolone or cheddar. Mixing in some parmesan can also add a nice flavor kick. Just ensure the cheese you choose melts well to maintain a creamy texture.

Can I make this casserole ahead of time?

Yes, this casserole can be prepared ahead of time. Assemble it, cover tightly, and refrigerate for up to 24 hours before baking. You may need to add a few extra minutes to the baking time if it's coming straight from the fridge.

Is it possible to freeze Chicken Parmesan Casserole?

Yes, you can freeze this casserole before baking. Wrap it tightly with plastic wrap and then foil to prevent freezer burn. It can be stored for up to three months. Thaw in the refrigerator overnight before baking, and enjoy!

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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