Enchilada Casserole

Prep: 10 min Cook: 30 min Serves: 6 Cuisine: Mexican

Enchilada Casserole is a comforting dish that layers savory ground chuck, zesty enchilada sauce, and creamy soups between soft tortillas, topped with melted cheese. Perfect for busy weeknights, this hearty meal satisfies the whole family with its bold flavors and easy preparation.

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Ingredients

  • 1 lb. ground chuck
  • 1 onion, chopped
  • 1 pkg. flour tortillas
  • 1 can enchilada sauce
  • 1 can cream of mushroom soup
  • 1 can cream of chicken soup
  • 6 oz. grated cheese

Instructions

  1. Brown beef and onions in microwave on High for 4 minutes. Drain if necessary.
  2. Stir to crumble meat.
  3. Add enchilada sauce and soups.
  4. In a 3-quart casserole dish, layer tortillas, meat mixture and cheese.
  5. Repeat layers, except cheese.
  6. Microwave on Medium about 20 minutes or until heated through.
  7. Top with grated cheese and let stand until melted.

Tips & Substitutions

For added flavor, consider seasoning the ground beef with taco seasoning or cumin before cooking. You can substitute ground turkey or chicken for a lighter option. If you're looking to make it vegetarian, use black beans or lentils instead of meat. Experiment with different types of cheese like pepper jack for some heat or cheddar for a classic taste.

Serving Suggestions

Serve the enchilada casserole with a side of Mexican rice and a fresh green salad for a complete meal. Garnish with chopped cilantro, sour cream, or sliced jalapeños for added flavor. This dish pairs beautifully with Chicken Enchilada Casserole for a festive family dinner.

Storage & Reheating

Store leftover enchilada casserole in an airtight container in the refrigerator for up to 3 days. To reheat, microwave individual portions on medium power for about 2-3 minutes or until warmed through. Alternatively, cover the casserole with foil and heat in a preheated oven at 350°F (175°C) for about 20 minutes.

Nutrition & Diet Analysis (per serving)

Each serving of Enchilada Casserole contains roughly 492 calories, with 21g protein, 45g carbohydrates, and 26g fat. It is an excellent source of protein (43% of the Daily Value) and iron (24% of the Daily Value), and a good source of potassium. Note that it is relatively high in sodium, at 1422mg per serving (62% of the Daily Value).

492 kcal 25% DV
Protein Fat Carbs

Macronutrients

Protein 21.4g 43% DV
Total Fat 25.7g 33% DV
Carbs 44.5g 16% DV
Fiber 2.5g 9% DV
Sugar 6.4g 13% DV

Electrolytes

Sodium 1421.5mg 62% DV
Potassium 459.6mg 10% DV
Cholesterol 56.7mg 19% DV

Vitamins & Minerals

Vitamin A 71.6mcg 8% DV
Vitamin C 1.5mg 2% DV
Vitamin D 0.1mcg
Calcium 113.6mg 9% DV
Iron 4.4mg 24% DV
Diet fit High-protein
Contains Milk Wheat/Gluten

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I make this enchilada casserole ahead of time?

Yes! You can prepare the casserole a day in advance. Simply assemble it without the cheese, cover, and refrigerate. When you're ready to cook, add the cheese on top and microwave or bake as directed. This makes it convenient for busy weeknights.

Can I use corn tortillas instead of flour?

Absolutely! Corn tortillas can be used in place of flour tortillas for a gluten-free option. Just be sure to slightly soften them in the microwave or on a skillet to prevent cracking when layering in the casserole.

What can I serve with enchilada casserole?

This dish goes well with refried beans, guacamole, or a tangy salsa. For a refreshing touch, serve with a simple avocado salad or a side of tortilla chips. Browse more Mexican recipes for additional side options to complement your meal.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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