Midwest Meat Loaf

Prep: 15 min Cook: 40 min Serves: 4 Cuisine: American

A comforting Midwest meat loaf featuring velvety cheese and a tangy ketchup glaze, perfect for family dinners and hearty gatherings with savory, cheesy flavors.

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Ingredients

  • 1/2 lb Velveeta cheese
  • 1/4 cup milk
  • 2 tbsp dry mustard
  • 1 lb ground beef
  • 1/3 cup oats (uncooked)
  • 1/4 cup ketchup
  • 1/4 cup onion, finely chopped

Instructions

  1. Stir Velveeta cheese, milk, and dry mustard in a small saucepan over low heat until smooth.
  2. Reserve 3/4 cup of the cheese mixture for the sauce.
  3. Mix the remaining cheese mixture with ground beef, oats, chopped onion, and ketchup in a large bowl until well blended.
  4. Shape the mixture into a loaf and place it in a loaf pan.
  5. Bake in a preheated oven at 350°F (175°C) for 40 minutes.
  6. Pour the reserved cheese sauce over the baked meatloaf and serve.

Tips & Substitutions

For a creamier texture, consider using a combination of Velveeta and cream cheese. You can swap ground beef with ground turkey for a lighter option. If you're out of oats, breadcrumbs work well too. For added flavor, try mixing in some Worcestershire sauce or herbs like parsley or thyme, enhancing the profile while staying true to classic American recipes.

Serving Suggestions

Serve this Midwest Meat Loaf with creamy mashed potatoes or buttery corn for a comforting meal. A fresh garden salad or roasted vegetables can provide a nice contrast. For a hearty dinner, pair it with crusty bread. This dish also pairs beautifully with Rick'S Favorite Hamburgers for a fun meat-themed dinner.

Storage & Reheating

To store leftovers, wrap the meatloaf tightly in plastic wrap or aluminum foil and refrigerate for up to 3-4 days. For longer storage, freeze it in an airtight container for up to 3 months. To reheat, thaw in the refrigerator overnight, then bake at 350°F (175°C) until heated through, or microwave slices until warm.

Nutrition & Diet Analysis (per serving)

Each serving of Midwest Meat Loaf contains roughly 647 calories, with 17g protein, 100g carbohydrates, and 20g fat. It is an excellent source of iron (45% of the Daily Value), calcium (44% of the Daily Value), and protein (33% of the Daily Value), and a good source of potassium and vitamin D. Note that it is relatively high in sodium, at 777mg per serving (34% of the Daily Value).

647 kcal 32% DV
Protein Fat Carbs

Macronutrients

Protein 16.7g 33% DV
Total Fat 20.2g 26% DV
Carbs 100.1g 36% DV
Fiber 2.3g 8% DV
Sugar 57g 100% DV

Electrolytes

Sodium 777mg 34% DV
Potassium 509.5mg 11% DV
Cholesterol 27.3mg 9% DV

Vitamins & Minerals

Vitamin A 217.9mcg 24% DV
Vitamin C 18.2mg 20% DV
Vitamin D 2mcg 10% DV
Calcium 567.3mg 44% DV
Iron 8.1mg 45% DV
Diet fit Low-fat
Contains Milk

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I prepare the meatloaf ahead of time?

Absolutely! You can prepare the meatloaf mixture a day in advance and refrigerate it before baking. Just shape it into a loaf, cover it, and store it in the fridge. When you're ready to cook, bake it directly from the fridge, adding a few extra minutes to the cooking time.

What can I use instead of Velveeta cheese?

If you prefer a different cheese, you can use cheddar or a blend of cheeses. Just ensure they melt well for a similar creamy consistency. Adding a bit of cream or milk to help it melt smoothly can mimic the texture of Velveeta.

How do I know when the meatloaf is done?

The best way to check is to use a meat thermometer. The internal temperature should reach 160°F (70°C) for ground beef. If you don't have a thermometer, you can cut into the center; it should no longer be pink, and the juices should run clear.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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