Oven Barbecue Brisket

Prep: 720 min Cook: 300 min Cuisine: American

Tender, smoky oven-baked brisket infused with rich barbecue flavors, perfect for gatherings or family dinners, offering a melt-in-your-mouth texture and savory taste.

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Ingredients

  • 5 to 6 lb boneless brisket
  • onion salt
  • garlic salt
  • celery salt
  • 3 oz liquid smoke
  • salt
  • pepper
  • Worcestershire sauce

Instructions

  1. Sprinkle the brisket with onion salt, garlic salt, and celery salt. Marinate overnight in liquid smoke.
  2. In the morning, sprinkle the meat with salt and pepper to taste, and add Worcestershire sauce.
  3. Wrap the brisket in heavy foil and bake in a preheated oven at 275°F (135°C) for about 5 hours or until the meat is tender.
  4. Baste the brisket with barbecue sauce and bake a little longer to heat through.
  5. Let the brisket cool slightly, then slice and serve.
  6. Reheat if necessary before serving.

Tips & Substitutions

For maximum flavor, marinate the brisket in liquid smoke for at least 12 hours. Adjust the seasoning with onion salt, garlic salt, and celery salt according to your taste. If you want a touch of sweetness, consider adding a brown sugar glaze before wrapping the brisket. For a smoky depth, use a mix of hickory and mesquite liquid smoke.

Serving Suggestions

Slice the brisket against the grain for tender pieces. It pairs beautifully with roasted vegetables, coleslaw, or baked beans. Consider serving it on a toasted bun for a hearty sandwich. For a complete meal, offer sides like cornbread or a fresh green salad, and complement with Aunt Jan's Brisket for more delicious inspiration.

Storage & Reheating

Store leftover brisket in an airtight container in the refrigerator for up to 4 days. To reheat, wrap it in foil and place it in a preheated oven at 250°F (120°C) until warmed through. Alternatively, you can slice and reheat individual pieces in a skillet over low heat, adding a splash of broth or water to keep it moist.

Nutrition & Diet Analysis (per serving)

Each serving of Oven Barbecue Brisket contains roughly 33 calories, with 2g protein, 6g carbohydrates, and 1g fat. Note that it is relatively high in sodium, at 630mg per serving (27% of the Daily Value).

33 kcal 2% DV
Protein Fat Carbs

Macronutrients

Protein 1.7g 3% DV
Total Fat 0.6g 1% DV
Carbs 6g 2% DV
Fiber 2.1g 7% DV
Sugar 3.3g 7% DV

Electrolytes

Sodium 630.3mg 27% DV
Potassium 373.5mg 8% DV
Cholesterol 1.6mg 1% DV

Vitamins & Minerals

Vitamin A 32.9mcg 4% DV
Vitamin C 7.8mg 9% DV
Vitamin D 0mcg
Calcium 55.3mg 4% DV
Iron 0.7mg 4% DV
Diet fit Keto-friendly Under 400 cal Low-fat

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I use a different cut of meat for this recipe?

Yes, you can substitute chuck roast or another cut of beef, but cooking times may vary. Ensure the meat is well-marbled for tenderness. Adjust cooking time to ensure it becomes tender.

How can I add more barbecue flavor?

To intensify the barbecue flavor, baste the brisket with your favorite barbecue sauce during the last hour of baking. You can also add a layer of sauce before serving for an extra kick.

Is it possible to cook this brisket recipe in a slow cooker?

Absolutely! You can cook the brisket in a slow cooker on low for 8-10 hours or high for 4-6 hours. Follow the same seasoning and marinating steps for great flavor, and add a little liquid smoke to the cooking liquid for that smoky essence.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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