Southwest Chicken Casserole

Prep: 15 min Cook: 45 min Serves: 6 Cuisine: Mexican

A hearty Southwest Chicken Casserole combining tender chicken, rice, and spicy tomatoes, topped with melted Cheddar cheese — perfect for a flavorful family dinner.

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Ingredients

  • 1 c. rice
  • 2 c. chicken stock
  • 1 c. cooked chicken, cut into strips
  • 1 medium onion, chopped
  • 10 oz. can Ro-Tel tomatoes and green chilies
  • 1 tsp. chili powder
  • 1 can cream of chicken soup
  • 1 c. sour cream
  • 16 oz. shredded Cheddar cheese

Instructions

  1. Cook rice in chicken stock until tender.
  2. Pour cooked rice into a 13 x 9-inch casserole dish.
  3. In a mixing bowl, combine cooked chicken, chopped onion, cream of chicken soup, sour cream, chili powder, and the can of Ro-Tel tomatoes and green chilies.
  4. Pour the mixture over the rice in the casserole dish.
  5. Top with shredded Cheddar cheese and the can of Ro-Tel tomatoes.
  6. Bake at 350°F for 45 minutes until hot and bubbly.

Tips & Substitutions

For added flavor, consider using leftover King Randi Chicken or Emery'S Ranch Chicken instead of cooked chicken. You can also replace the cream of chicken soup with a homemade version for a healthier option. Adjust the amount of chili powder based on your spice preference, and feel free to add black beans or corn for extra texture.

Serving Suggestions

This casserole pairs beautifully with a simple green salad or Mexican rice for a complete meal. You can also serve it with tortilla chips for a crunchy contrast. Consider topping with fresh cilantro, avocado slices, or a dollop of guacamole for added richness and flavor.

Storage & Reheating

Store any leftover Southwest Chicken Casserole in an airtight container in the refrigerator for up to 3 days. To reheat, place in the oven at 350°F until heated through, about 20-25 minutes. You can also microwave individual portions, covering with a damp paper towel to keep moisture.

Nutrition & Diet Analysis (per serving)

Each serving of Southwest Chicken Casserole contains roughly 573 calories, with 20g protein, 88g carbohydrates, and 17g fat. It is an excellent source of protein (40% of the Daily Value), vitamin A (31% of the Daily Value), and iron (26% of the Daily Value), and a good source of dietary fiber and potassium. Note that it is relatively high in sodium, at 1937mg per serving (84% of the Daily Value).

573 kcal 29% DV
Protein Fat Carbs

Macronutrients

Protein 19.9g 40% DV
Total Fat 17.1g 22% DV
Carbs 88.2g 32% DV
Fiber 5.3g 19% DV
Sugar 4.6g 9% DV

Electrolytes

Sodium 1937mg 84% DV
Potassium 540.2mg 11% DV
Cholesterol 33.5mg 11% DV

Vitamins & Minerals

Vitamin A 282.3mcg 31% DV
Vitamin C 0.9mg 1% DV
Vitamin D 0.1mcg 1% DV
Calcium 287.7mg 22% DV
Iron 4.7mg 26% DV
Diet fit High-fiber Low-fat
Contains Milk

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I use brown rice instead of white rice?

Yes, you can use brown rice, but be sure to adjust the cooking time and liquid accordingly, as brown rice typically requires more water and a longer cooking time. Pre-cooking the brown rice slightly may also help balance the dish.

Is it possible to freeze this casserole?

Absolutely! You can freeze the casserole before baking. Just assemble it in a freezer-safe dish, cover tightly, and store for up to 3 months. When ready to bake, thaw in the refrigerator overnight and bake as directed.

What can I substitute for sour cream?

If you want a lighter option, Greek yogurt can be used in place of sour cream. It will give a similar tangy flavor while adding protein. Alternatively, a dairy-free yogurt can work for a non-dairy option.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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