24 Hour Chicken Casserole

Prep: 15 min Cook: 75 min Serves: 8 Cuisine: American

A hearty and creamy chicken casserole combining macaroni, Velveeta cheese, and mushrooms, perfect for comforting family dinners or potlucks with rich flavors and satisfying textures.

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Ingredients

  • 1 3/4 cups uncooked macaroni
  • 2 cups cooked cut-up chicken
  • Salt and pepper to taste
  • 2 cans mushroom soup
  • 1/2 pound cubed Velveeta cheese
  • 3 hard-cooked eggs cubed
  • 2 cups milk

Instructions

  1. Combine uncooked macaroni, cooked cut-up chicken, mushroom soup, cubed Velveeta cheese, cubed hard-cooked eggs, and milk in a large bowl.
  2. Season with salt and pepper to taste.
  3. Transfer the mixture to a 9 x 13-inch pan.
  4. Refrigerate overnight.
  5. Bake at 350°F for 1 1/4 hours until heated through and bubbly.

Tips & Substitutions

For a creamier texture, consider adding a bit of sour cream or cream cheese to the mixture. If you prefer a healthier option, swap out Velveeta cheese for a reduced-fat cheese or a dairy-free alternative. You can also incorporate vegetables like peas or spinach for added nutrition. This dish can easily be customized to include leftover veggies from other meals.

Serving Suggestions

This 24 Hour Chicken Casserole is delicious on its own but pairs beautifully with a crisp green salad or steamed broccoli for a complete meal. For a heartier option, serve it with garlic bread or a side of roasted vegetables. It can also be a great dish for potlucks or family gatherings, as it is easy to prepare in advance.

Storage & Reheating

Store any leftover casserole in an airtight container in the refrigerator for up to 3 days. To reheat, place individual portions in the microwave for about 2-3 minutes or until heated through. Alternatively, reheat in the oven at 350°F for 15-20 minutes, covered with foil to prevent drying out.

Nutrition & Diet Analysis (per serving)

Each serving of 24 Hour Chicken Casserole contains roughly 272 calories, with 11g protein, 39g carbohydrates, and 8g fat. It is an excellent source of protein (22% of the Daily Value), and a good source of calcium and iron. Note that it is relatively high in sodium, at 1823mg per serving (79% of the Daily Value).

272 kcal 14% DV
Protein Fat Carbs

Macronutrients

Protein 11g 22% DV
Total Fat 8.3g 11% DV
Carbs 38.5g 14% DV
Fiber 0.9g 3% DV
Sugar 14.7g 29% DV

Electrolytes

Sodium 1822.6mg 79% DV
Potassium 239.4mg 5% DV
Cholesterol 18.1mg 6% DV

Vitamins & Minerals

Vitamin A 67mcg 7% DV
Vitamin C 6.3mg 7% DV
Vitamin D 0.5mcg 2% DV
Calcium 215.1mg 17% DV
Iron 2.8mg 16% DV
Diet fit Under 400 cal Low-fat
Contains Milk Egg

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I use different types of cheese in this casserole?

Yes, you can substitute Velveeta cheese with other types of cheese such as cheddar, Monterey Jack, or a blend of your favorites. Just keep in mind that the texture and flavor may vary depending on the cheese you choose.

Is it necessary to refrigerate the casserole overnight?

Refrigerating the casserole overnight allows the flavors to meld together, enhancing the overall taste. However, if you're short on time, you can bake it right away, but it may not be as flavorful.

Can I add vegetables to this casserole?

Absolutely! Adding vegetables like broccoli, bell peppers, or carrots can enhance the nutritional value and flavor of the casserole. Just make sure to chop them small enough to ensure they cook through during baking.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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