Laster'S Best Chicken Casserole

Prep: 15 min Cook: 35 min Serves: 6 Cuisine: American

A cheesy, flavorful chicken casserole layered with Doritos, creamy soups, and cheese, perfect for a comforting family dinner with bold Tex-Mex-inspired flavors.

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Ingredients

  • 1 cooked and boned chicken
  • 1 can cream of chicken soup
  • 1 can Ro-Tel diced tomatoes
  • 1 1/2 cups chicken broth
  • 1 (15 1/2 oz.) bag Doritos
  • 1/2 cup grated cheese
  • 1 chopped onion
  • 1 can cream of mushroom soup

Instructions

  1. Mix the cream of chicken soup, cream of mushroom soup, Ro-Tel tomatoes, chicken broth, and chopped onion.
  2. In a 3-quart casserole dish, layer Doritos, the soup mixture, and cooked, boned chicken, repeating layers as needed.
  3. Bake at 350°F for 30 minutes.
  4. Top with grated cheese and return to oven for 5 minutes to melt the cheese.

Tips & Substitutions

For a creamier texture, consider adding a dollop of sour cream to the soup mixture. If you prefer a milder flavor, use a can of diced tomatoes without green chilies instead of Ro-Tel. You can substitute the Doritos with crushed tortilla chips or even homemade tortilla strips for a healthier twist. Feel free to add vegetables like bell peppers or corn for extra nutrition.

Serving Suggestions

This casserole pairs beautifully with a fresh green salad or steamed vegetables for a balanced meal. For a comforting dinner, serve it alongside garlic bread or cornbread. You might also consider offering a side of rice, which complements the flavors well. This dish is perfect for potlucks or family gatherings, providing hearty servings for everyone.

Storage & Reheating

Store any leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, place the casserole in a preheated oven at 350°F for about 20 minutes or until heated through. You can also microwave individual portions for 2-3 minutes, ensuring they're heated evenly.

Nutrition & Diet Analysis (per serving)

Each serving of Laster'S Best Chicken Casserole contains roughly 272 calories, with 8g protein, 28g carbohydrates, and 15g fat. It is a good source of protein (15% of the Daily Value). Note that it is relatively high in sodium, at 837mg per serving (36% of the Daily Value).

272 kcal 14% DV
Protein Fat Carbs

Macronutrients

Protein 7.6g 15% DV
Total Fat 14.7g 19% DV
Carbs 28.5g 10% DV
Fiber 1.6g 6% DV
Sugar 5.7g 11% DV

Electrolytes

Sodium 837.3mg 36% DV
Potassium 188.5mg 4% DV
Cholesterol 11.9mg 4% DV

Vitamins & Minerals

Vitamin A 23.4mcg 3% DV
Vitamin C 1.4mg 2% DV
Vitamin D 0mcg
Calcium 95.4mg 7% DV
Iron 1.3mg 7% DV
Diet fit Under 400 cal
Contains Milk

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I use leftover rotisserie chicken for this recipe?

Absolutely! Leftover rotisserie chicken adds great flavor and saves time. Just shred the chicken and incorporate it into the layers as directed. It’s a convenient way to make this casserole even quicker and easier, especially on busy weeknights.

Is it possible to make this casserole ahead of time?

Yes, you can prepare the casserole a day in advance. Layer all the ingredients in the dish, cover it tightly with plastic wrap, and store it in the fridge. When ready to bake, remove the wrap and bake as instructed, adding a few extra minutes if it's coming straight from the refrigerator.

Can I freeze this chicken casserole?

Yes, you can freeze the casserole before baking. Assemble it in a freezer-safe dish, cover tightly, and freeze for up to 2 months. When ready to cook, thaw it in the refrigerator overnight, then bake as directed. This is a great way to enjoy a homemade meal at a later date.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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