Ohio Lasagna

Prep: 20 min Cook: 60 min Serves: 13 Cuisine: American

Ohio Lasagna features layers of savory meat sauce, creamy cheeses, and tender noodles, creating a hearty, cheesy dish perfect for family gatherings and comfort food lovers.

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Ingredients

  • 1 1/2 lb. ground chuck
  • 1 (16 oz.) package lasagna noodles
  • 1/2 lb. American cheese
  • 1/2 lb. grated mozzarella cheese
  • Parmesan cheese (to taste)
  • 1 medium onion, chopped
  • 1 (2 oz.) can mushrooms
  • 1 family size can tomato sauce
  • 2 (8 oz.) cans tomato paste
  • Basil leaves (to taste)

Instructions

  1. Brown ground chuck in a skillet.
  2. Add chopped onion, canned mushrooms, tomato sauce, and tomato paste. Simmer for 30 minutes.
  3. Prepare lasagna noodles separately using a tablespoon of oil in boiling water to prevent sticking.
  4. Drain the noodles and spread each noodle flat.
  5. Layer the sauce, noodles, and cheeses in a 13 x 9 1/4-inch casserole dish.
  6. Repeat the layering process until all ingredients are used.
  7. Top with American cheese, grated mozzarella, and Parmesan cheese to taste.
  8. Cover and bake at 350°F for 30 minutes.

Tips & Substitutions

To enhance your Ohio Lasagna, consider adding a pinch of red pepper flakes for a subtle kick or substituting cottage cheese for part of the American cheese for a creamier texture. You can also use no-boil lasagna noodles to save time. For a vegetarian version, replace the ground chuck with sautéed vegetables or lentils, making it a satisfying option for those exploring vegetarian recipes.

Serving Suggestions

Ohio Lasagna pairs beautifully with a crisp side salad and garlic bread to round out the meal. For a comforting touch, serve it alongside a warm bowl of Deluxe Broccoli Casserole. A light dessert, such as Chocolate Cake, can be a delightful way to finish the meal, balancing the hearty flavors of the lasagna.

Storage & Reheating

Store leftovers in an airtight container in the refrigerator for up to 4 days. To reheat, place individual servings in the microwave for 2-3 minutes, or cover and bake in the oven at 350°F for about 20 minutes until heated through. If the lasagna seems dry, add a splash of tomato sauce before reheating.

Nutrition & Diet Analysis (per serving)

Each serving of Ohio Lasagna contains roughly 134 calories, with 10g protein, 12g carbohydrates, and 6g fat. It is an excellent source of protein (20% of the Daily Value), and a good source of calcium and vitamin A.

134 kcal 7% DV
Protein Fat Carbs

Macronutrients

Protein 10g 20% DV
Total Fat 6.1g 8% DV
Carbs 11.6g 4% DV
Fiber 2.2g 8% DV
Sugar 5.2g 10% DV

Electrolytes

Sodium 259.7mg 11% DV
Potassium 549mg 12% DV
Cholesterol 18.2mg 6% DV

Vitamins & Minerals

Vitamin A 161.3mcg 18% DV
Vitamin C 14.2mg 16% DV
Vitamin D 1.2mcg 6% DV
Calcium 234.1mg 18% DV
Iron 2.5mg 14% DV
Diet fit Keto-friendly Under 400 cal
Contains Milk Wheat/Gluten

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I make Ohio Lasagna ahead of time?

Yes, you can assemble the lasagna a day in advance. Cover it tightly with plastic wrap and refrigerate. When you're ready to bake, simply remove the wrap and bake at 350°F, possibly adding an extra 10-15 minutes to the cooking time if baking from cold.

What can I use instead of ground chuck?

If you're looking for alternatives to ground chuck, you can use ground turkey or chicken for a leaner option. For a vegetarian alternative, consider crumbled tempeh or a mix of sautéed mushrooms and zucchini, which will still provide a hearty texture.

How do I prevent the noodles from sticking together?

To prevent the lasagna noodles from sticking, add a tablespoon of oil to the boiling water before cooking. Stir the noodles occasionally while cooking, and after draining, lay them flat on a clean kitchen towel or parchment paper to cool slightly before layering.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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