Quick And Easy Pepperoni Bread

Prep: 20 min Cook: 25 min Serves: 8 Cuisine: American

A savory, cheesy pepperoni-filled bread that's quick to prepare and perfect for sharing at parties or family dinners, offering gooey cheese, spicy pepperoni, and flavorful sauce.

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Ingredients

  • 1 loaf frozen bread dough
  • 3 to 4 oz. sliced pepperoni
  • 4 to 6 oz. shredded Mozzarella cheese
  • 2 to 3 Tbsp. grated Parmesan cheese
  • 1/2 cup spaghetti or pizza sauce
  • sauteed pepper and/or onions (optional)

Instructions

  1. Thaw the frozen bread dough.
  2. Pat the dough into a 12 x 15-inch rectangle on a floured surface.
  3. Spread spaghetti or pizza sauce in the middle of the rectangle.
  4. Layer sliced pepperoni evenly in several layers in the middle, about 3 to 4 inches of the dough rectangle.
  5. Sprinkle shredded Mozzarella cheese and grated Parmesan over the pepperoni.
  6. Fold the dough lengthwise to enclose the filling, pinching the seams well.
  7. Pinch and seal the ends of the dough.
  8. Place the seam side down on a greased baking sheet.
  9. Bake at 350°F (175°C) for 25 minutes until golden brown.

Tips & Substitutions

For a twist on flavor, consider adding some sautéed peppers or onions to the filling. If you want a bit more spice, try adding some crushed red pepper flakes. You can also substitute the Mozzarella with other cheeses like Provolone or Cheddar for a different taste. Make sure to let the dough rest and rise appropriately before baking for the best texture.

Serving Suggestions

Serve this delicious pepperoni bread with a side of marinara or ranch dressing for dipping. It makes a great appetizer for gatherings or a fun addition to a game day spread. Pair it with a fresh salad or some veggies for a balanced meal. For dessert, consider making a Quick Lemon Tart to finish off the meal on a sweet note.

Storage & Reheating

Store any leftover pepperoni bread in an airtight container in the refrigerator for up to three days. To reheat, simply place it in a preheated oven at 350°F (175°C) for about 10-15 minutes until warmed through. You can also microwave individual slices for quick reheating, but the oven will help maintain the crispy exterior.

Nutrition & Diet Analysis (per serving)

Each serving of Quick And Easy Pepperoni Bread contains roughly 179 calories, with 11g protein, 17g carbohydrates, and 8g fat. It is an excellent source of vitamin C (51% of the Daily Value), protein (22% of the Daily Value), and calcium (20% of the Daily Value).

179 kcal 9% DV
Protein Fat Carbs

Macronutrients

Protein 11.2g 22% DV
Total Fat 7.6g 10% DV
Carbs 17.2g 6% DV
Fiber 2.6g 9% DV
Sugar 3g 6% DV

Electrolytes

Sodium 437.4mg 19% DV
Potassium 371.2mg 8% DV
Cholesterol 23.5mg 8% DV

Vitamins & Minerals

Vitamin A 81.5mcg 9% DV
Vitamin C 45.8mg 51% DV
Vitamin D 0.1mcg 1% DV
Calcium 264.2mg 20% DV
Iron 1.2mg 7% DV
Diet fit Low-carb Under 400 cal
Contains Milk Wheat/Gluten

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I use homemade bread dough instead of frozen?

Absolutely! If you prefer homemade bread dough, you can make it from scratch and follow the same steps for filling and baking. Homemade dough may yield a fresher flavor and texture, so it’s a great option if you have the time to prepare it in advance.

What can I do with leftovers?

Leftover pepperoni bread can be sliced and enjoyed cold or reheated. You can also chop it up and add it to salads or pasta dishes for added flavor. If you have a lot left, consider freezing individual portions for quick snacks later on.

Can I customize the fillings?

Yes! Feel free to customize the fillings based on your preferences. You can add vegetables like mushrooms, spinach, or olives, or substitute the pepperoni with Italian sausage or ham for a different flavor. This versatility makes it easy to cater to different tastes.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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