Sicilian Casserole

Prep: 20 min Cook: 45 min Serves: 8 Cuisine: Italian

A hearty Sicilian casserole blending savory meats, vibrant vegetables, and melted cheese, perfect for family dinners and comforting gatherings with bold flavors.

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Ingredients

  • 1/2 lb. ground beef
  • 1/2 lb. ground hot sausage
  • 1 green pepper, diced
  • 1 onion, diced
  • 1 1/2 qt. spaghetti sauce
  • 1 lb. pasta (wheels, corkscrews, or other)
  • 1/2 lb. pepperoni
  • 1 small can mushroom pieces, drained
  • 8 oz. shredded Mozzarella cheese

Instructions

  1. Brown the ground beef, hot sausage, diced green pepper, and diced onion in a skillet until cooked through. Drain excess grease.
  2. Spread 1/2 of the spaghetti sauce in the bottom of a 9 x 13-inch baking dish.
  3. Layer half of the cooked pasta over the sauce.
  4. Add the sliced pepperoni evenly over the pasta.
  5. Distribute the drained mushroom pieces and half of the shredded mozzarella cheese over the pepperoni.
  6. Add the remaining cooked pasta, followed by the rest of the spaghetti sauce.
  7. Sprinkle the remaining shredded mozzarella cheese on top.
  8. Cover the dish with foil and bake at 350°F for 30 minutes.
  9. Uncover and bake for an additional 15 minutes until bubbly and golden.

Tips & Substitutions

For a variation, try using ground turkey or chicken instead of beef and sausage for a lighter dish. You can also substitute the pasta with gluten-free options if needed. If you prefer a spicier kick, add some crushed red pepper flakes to the meat mixture. This casserole is a great way to use up leftover meat or vegetables, making it versatile and practical.

Serving Suggestions

This Sicilian Casserole pairs beautifully with a fresh garden salad and garlic bread for a complete meal. You can also serve it alongside roasted vegetables or a simple antipasto platter for an Italian-inspired feast. For a fun twist, consider serving with a side of Italian recipes like bruschetta or stuffed peppers.

Storage & Reheating

Store leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, cover with foil and bake at 350°F until heated through, about 20-25 minutes. You can also microwave individual portions, but be sure to cover them to retain moisture and heat evenly.

Nutrition & Diet Analysis (per serving)

Each serving of Sicilian Casserole contains roughly 719 calories, with 49g protein, 17g carbohydrates, and 49g fat. It is an excellent source of vitamin A (214% of the Daily Value), protein (98% of the Daily Value), and iron (61% of the Daily Value), and a good source of calcium and potassium. Note that it is relatively high in sodium, at 627mg per serving (27% of the Daily Value).

719 kcal 36% DV
Protein Fat Carbs

Macronutrients

Protein 49g 98% DV
Total Fat 49.5g 63% DV
Carbs 16.9g 6% DV
Fiber 1.5g 5% DV
Sugar 2.8g 6% DV

Electrolytes

Sodium 626.9mg 27% DV
Potassium 808.7mg 17% DV
Cholesterol 241.8mg 81% DV

Vitamins & Minerals

Vitamin A 1923.8mcg 100% DV
Vitamin C 18.1mg 20% DV
Vitamin D 4mcg 20% DV
Calcium 248.7mg 19% DV
Iron 11mg 61% DV
Diet fit High-protein Low-carb
Contains Milk Wheat/Gluten

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I make this casserole ahead of time?

Yes, you can assemble the casserole a day in advance. Cover it tightly with foil and store it in the refrigerator. When ready to bake, allow it to come to room temperature before placing it in the oven to ensure even cooking.

What type of pasta works best for this recipe?

You can use any short pasta shape, such as wheels or corkscrews, which hold the sauce well. However, feel free to experiment with other shapes like penne or fusilli. Just make sure to cook the pasta slightly less than al dente, as it will continue to cook while baking.

Can I freeze this casserole?

Absolutely! To freeze, assemble the casserole but do not bake it. Cover tightly with plastic wrap and aluminum foil, and it will keep for up to 3 months. When ready to bake, thaw in the refrigerator overnight and then bake as directed for a comforting meal any time.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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