Tex-Mex Spaghetti Casserole

Prep: 15 min Cook: 30 min Serves: 6 Cuisine: Mexican

A flavorful Tex-Mex spaghetti casserole combining seasoned beef, cheesy topping, and pasta, perfect for a family-friendly meal with bold southwestern flavors.

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Ingredients

  • 1 lb. ground beef
  • 1 pkg. taco seasoning mix
  • 1/4 c. chopped onions
  • 1 (8 oz.) can tomato sauce
  • 1 (7 oz.) pkg. spaghetti
  • 1 c. shredded cheese

Instructions

  1. Cook spaghetti according to package directions; drain and place in the bottom of a 9 x 13-inch baking dish.
  2. Set aside.
  3. Brown ground beef and chopped onions; drain excess fat.
  4. Add taco seasoning mix and tomato sauce to the beef; mix well.
  5. Pour beef mixture over the cooked noodles.
  6. Sprinkle shredded cheese on top.
  7. Bake uncovered in a 350°F oven until cheese is melted.

Tips & Substitutions

For a spicier kick, add diced jalapeños or a splash of hot sauce to the beef mixture. If you want a lighter option, swap ground beef for ground turkey or a plant-based meat alternative. Consider using whole wheat spaghetti for added fiber. If you're in a hurry, pre-cooked spaghetti can save time. Also, this dish can be easily customized with your favorite vegetables like bell peppers or corn.

Serving Suggestions

This Tex-Mex Spaghetti Casserole pairs beautifully with a fresh Mexican Salad Bowl for a refreshing contrast. Serve with sour cream or guacamole on the side to enhance the flavors. For a complete meal, consider adding a side of Easy Enchilada Dish or some tortilla chips for crunch. A light green salad also complements the richness of the casserole.

Storage & Reheating

Store leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, place in an oven-safe dish and cover with foil to prevent drying out, then heat at 350°F until warmed through, approximately 20-25 minutes. You can also microwave individual portions for a quick meal, adding a splash of water to keep it moist.

Nutrition & Diet Analysis (per serving)

Each serving of Tex-Mex Spaghetti Casserole contains roughly 378 calories, with 17g protein, 45g carbohydrates, and 14g fat. It is an excellent source of protein (33% of the Daily Value), and a good source of iron and dietary fiber. Note that it is relatively high in sodium, at 1025mg per serving (45% of the Daily Value).

378 kcal 19% DV
Protein Fat Carbs

Macronutrients

Protein 16.5g 33% DV
Total Fat 13.7g 18% DV
Carbs 45.2g 16% DV
Fiber 4.3g 15% DV
Sugar 5.2g 10% DV

Electrolytes

Sodium 1024.7mg 45% DV
Potassium 410.6mg 9% DV
Cholesterol 27.1mg 9% DV

Vitamins & Minerals

Vitamin A 21.5mcg 2% DV
Vitamin C 3.4mg 4% DV
Vitamin D 0mcg
Calcium 87mg 7% DV
Iron 2.8mg 16% DV
Diet fit Under 400 cal
Contains Milk

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I make this casserole ahead of time?

Yes, you can prepare the casserole up to the baking step, cover it tightly, and refrigerate for up to 24 hours. When you're ready to bake it, simply add an extra 10-15 minutes to the baking time since it will be coming from the fridge.

What can I use instead of taco seasoning?

You can make your own taco seasoning using cumin, paprika, garlic powder, onion powder, and chili powder. This allows you to control the spice level and avoid additives found in pre-packaged mixes. Alternatively, Cajun seasoning can provide a unique flavor twist.

Is it possible to freeze this casserole?

Yes, you can freeze the assembled casserole before baking. Wrap it tightly in plastic wrap and aluminum foil to prevent freezer burn. It can be stored for up to 3 months. When ready to eat, thaw in the refrigerator overnight and bake as directed, adding a few extra minutes if needed.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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