T.G.I.F. Casserole

Prep: 15 min Cook: 60 min Serves: 6 Cuisine: Mexican

A hearty casserole layered with tortillas, seasoned ground beef, beans, and melted cheese, baked to perfection—ideal comfort food for family dinners or casual gatherings.

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Ingredients

  • 1 small package flour tortillas
  • 1.5 pounds ground beef
  • 1 pound Cheddar cheese, grated
  • 1 or 2 cans Ranch Style beans
  • 1.5 onions, chopped
  • 1 can Ro-Tel tomatoes
  • 1 can cream of chicken soup
  • Salt and pepper to taste

Instructions

  1. Brown ground beef and chopped onions in a skillet.
  2. Spray a casserole dish with Pam or cooking spray.
  3. Layer the dish with flour tortillas, then the cooked meat and onions.
  4. Add a layer of Ranch Style beans, then sprinkle grated Cheddar cheese on top.
  5. Mix together the Ro-Tel tomatoes and cream of chicken soup, then pour over the layered ingredients.
  6. Add an additional layer of tortillas on top to form a crust.
  7. Bake at 350°F (175°C) for 1 hour until bubbly and golden.

Tips & Substitutions

For a spicier kick, consider adding diced jalapeños or using spicy Ro-Tel tomatoes. You can substitute ground turkey or chicken for a lighter option. If you don't have Ranch Style beans, black beans or pinto beans work well too. For a twist, add some corn or bell peppers to the layers to enhance the flavor and texture. This recipe is also versatile; feel free to make it vegetarian by omitting the meat.

Serving Suggestions

Serve this hearty casserole with a side of fresh guacamole or a simple green salad to balance the richness. It pairs beautifully with Southwestern Chicken Salad Wraps for a complete meal. You can also top individual servings with sour cream, fresh cilantro, or diced avocado for added flavor. For a fun twist, serve with tortilla chips on the side.

Storage & Reheating

Store leftovers in an airtight container in the refrigerator for up to 3-4 days. To reheat, cover the casserole with foil and warm it in the oven at 350°F (175°C) until heated through, about 20-25 minutes. You can also microwave individual portions for quick reheating, but be sure to cover them to retain moisture.

Nutrition & Diet Analysis (per serving)

Each serving of T.G.I.F. Casserole contains roughly 658 calories, with 28g protein, 70g carbohydrates, and 29g fat. It is an excellent source of protein (57% of the Daily Value), iron (32% of the Daily Value), and dietary fiber (28% of the Daily Value), and a good source of calcium and potassium. Note that it is relatively high in sodium, at 2058mg per serving (89% of the Daily Value).

658 kcal 33% DV
Protein Fat Carbs

Macronutrients

Protein 28.4g 57% DV
Total Fat 29.2g 37% DV
Carbs 69.6g 25% DV
Fiber 8g 28% DV
Sugar 1.6g 3% DV

Electrolytes

Sodium 2058.4mg 89% DV
Potassium 688.6mg 15% DV
Cholesterol 65.2mg 22% DV

Vitamins & Minerals

Vitamin A 66mcg 7% DV
Vitamin C 0.5mg 1% DV
Vitamin D 0.2mcg 1% DV
Calcium 190.1mg 15% DV
Iron 5.7mg 32% DV
Diet fit High-protein High-fiber
Contains Milk Wheat/Gluten

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I make this casserole ahead of time?

Yes, you can assemble the casserole a day in advance and store it in the refrigerator until you're ready to bake it. Just be sure to cover it tightly with plastic wrap or aluminum foil to prevent it from drying out. Bake it straight from the fridge, adding a few extra minutes to the cooking time if needed.

What can I use instead of cream of chicken soup?

If you want to avoid cream of chicken soup, you can use a homemade cream sauce or a can of cream of mushroom soup as a substitute. Alternatively, a mixture of sour cream and chicken broth can create a similar creamy texture and flavor. Just adjust the seasoning accordingly to match your taste.

Is this recipe suitable for freezing?

Absolutely! You can freeze the casserole before or after baking. If freezing before baking, wrap it tightly in plastic wrap and foil to prevent freezer burn. When ready to enjoy, thaw it in the refrigerator overnight and bake as usual. If already baked, reheat from frozen, increasing the baking time to ensure it's heated through.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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