Barbecue Beef Bake

Prep: 10 min Cook: 20 min Serves: 4 Cuisine: American

A hearty and cheesy baked dish featuring flavorful barbecue beef layered with a biscuit topping, perfect for casual family dinners or entertaining friends.

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Ingredients

  • 1 lb. ground beef
  • 3/4 c. chopped onion
  • 18 oz. barbecue sauce
  • 2 c. shredded Cheddar cheese
  • 2 c. Bisquick
  • 1 c. milk
  • 2 eggs

Instructions

  1. Heat oven to 400°F.
  2. Cook ground beef and 1/2 cup of the chopped onion in a 10-inch skillet until beef is brown; drain excess fat.
  3. Stir in barbecue sauce.
  4. Spoon the beef mixture into an ungreased 13 x 9 x 2-inch baking dish.
  5. Sprinkle shredded Cheddar cheese over the top.
  6. In a bowl, combine Bisquick, milk, and eggs; mix until smooth.
  7. Pour the batter evenly over the cheese layer.
  8. Bake uncovered at 400°F for about 20 minutes or until the biscuit topping is golden brown.

Tips & Substitutions

For added flavor, consider sautéing the remaining onion with a teaspoon of garlic before adding it to the beef. You can substitute ground turkey or chicken for the beef for a lighter option. If you're out of Bisquick, a homemade biscuit mix can work as well. Adjust the barbecue sauce to your taste; try a smoky variety for a richer flavor.

Serving Suggestions

Serve the Barbecue Beef Bake with a fresh green salad or coleslaw for a balanced meal. It pairs beautifully with Easy Hamburger Goulash for a hearty dinner. Consider adding a side of cornbread or baked beans to round out the meal. This dish also works well for potlucks or family gatherings.

Storage & Reheating

Store any leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, place the bake in the oven at 350°F for about 15-20 minutes, or until heated through. You can also microwave portions, covering them to retain moisture, for about 2-3 minutes.

Nutrition & Diet Analysis (per serving)

Each serving of Barbecue Beef Bake contains roughly 1543 calories, with 61g protein, 148g carbohydrates, and 79g fat. It is an excellent source of protein (123% of the Daily Value), calcium (104% of the Daily Value), and vitamin A (65% of the Daily Value), and a good source of dietary fiber and vitamin C. Note that it is relatively high in sodium, at 2411mg per serving (105% of the Daily Value).

1543 kcal 77% DV
Protein Fat Carbs

Macronutrients

Protein 61.3g 100% DV
Total Fat 79.4g 100% DV
Carbs 147.8g 54% DV
Fiber 4.3g 15% DV
Sugar 52.6g 100% DV

Electrolytes

Sodium 2410.6mg 100% DV
Potassium 1073.5mg 23% DV
Cholesterol 305.8mg 100% DV

Vitamins & Minerals

Vitamin A 587.7mcg 65% DV
Vitamin C 11.6mg 13% DV
Vitamin D 2.1mcg 10% DV
Calcium 1348.9mg 100% DV
Iron 8.1mg 45% DV
Diet fit High-protein
Contains Milk Egg

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I make this dish ahead of time?

Yes, you can prepare the beef mixture and layer it in the baking dish earlier in the day. Cover it tightly and refrigerate. When ready to serve, make the biscuit topping, pour it over, and bake as directed. This saves time and allows the flavors to meld.

What can I use instead of Cheddar cheese?

If you don't have Cheddar, feel free to substitute with Monterey Jack, Pepper Jack for a kick, or even a blend of cheeses like mozzarella and Gouda. Each will add a unique flavor to the dish while still providing that creamy texture.

Can I freeze the leftovers?

Yes, you can freeze the Barbecue Beef Bake. Allow it to cool completely, then wrap it tightly in plastic wrap and foil or place it in a freezer-safe container. It can be stored for up to 3 months. Thaw in the refrigerator overnight before reheating.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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