Layered Spinach Supreme

Prep: 15 min Cook: 30 min Serves: 8 Cuisine: American

Layered Spinach Supreme is a savory casserole combining tender spinach, cheesy goodness, and a fluffy Bisquick batter, perfect for a hearty family meal or brunch.

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Ingredients

  • 1 cup Bisquick
  • 1/4 cup milk
  • 2 eggs
  • 1/4 cup chopped onion
  • 1 (10 oz) package chopped spinach, thawed and drained
  • 1/2 cup Parmesan cheese
  • 4 oz Monterey Jack cheese, cut in 1/2-inch cubes
  • 12 oz cottage cheese
  • 1/2 teaspoon salt

Instructions

  1. Combine Bisquick, milk, eggs, and chopped onion in a bowl.
  2. Mix well and spread the batter in a greased 12 x 7-inch pan.
  3. Combine chopped spinach, Parmesan cheese, cubed Monterey Jack cheese, cottage cheese, and salt.
  4. Spoon the spinach and cheese mixture over the batter in the pan.
  5. Bake at 375°F for 30 minutes until golden and set.

Tips & Substitutions

For a creamier texture, consider using ricotta cheese instead of cottage cheese. You can also add some garlic powder or fresh herbs like dill or parsley for extra flavor. If you want to make this dish gluten-free, substitute Bisquick with a gluten-free baking mix. Make sure to thoroughly squeeze the spinach to remove excess moisture before adding it to the cheese mixture.

Serving Suggestions

This Layered Spinach Supreme pairs beautifully with a fresh side salad or roasted vegetables for a complete meal. For a heartier option, serve it alongside grilled chicken or fish. You can also enjoy it as a main course with a slice of crusty bread. It’s a great dish to bring to potlucks or family gatherings.

Storage & Reheating

Store leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, place individual portions in the microwave for 1-2 minutes, or warm the entire dish in a preheated oven at 350°F until heated through. Cover with foil to prevent drying out during reheating.

Nutrition & Diet Analysis (per serving)

Each serving of Layered Spinach Supreme contains roughly 381 calories, with 11g protein, 58g carbohydrates, and 12g fat. It is an excellent source of calcium (26% of the Daily Value), iron (22% of the Daily Value), and protein (21% of the Daily Value), and a good source of vitamin A and vitamin C. Note that it is relatively high in sodium, at 646mg per serving (28% of the Daily Value).

381 kcal 19% DV
Protein Fat Carbs

Macronutrients

Protein 10.6g 21% DV
Total Fat 12.3g 16% DV
Carbs 57.6g 21% DV
Fiber 1.3g 5% DV
Sugar 22.3g 45% DV

Electrolytes

Sodium 645.6mg 28% DV
Potassium 373.8mg 8% DV
Cholesterol 40.3mg 13% DV

Vitamins & Minerals

Vitamin A 172.5mcg 19% DV
Vitamin C 11.4mg 13% DV
Vitamin D 0.7mcg 4% DV
Calcium 337.1mg 26% DV
Iron 4mg 22% DV
Diet fit Under 400 cal Low-fat
Contains Milk Egg

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I use fresh spinach instead of frozen?

Yes, you can use fresh spinach. You'll need about 1 pound of fresh spinach to replace the 10 oz package of frozen. Cook it down in a pan until wilted, then drain and chop it before mixing it with the cheese.

What can I substitute for Parmesan cheese?

If you don't have Parmesan cheese, you can substitute it with Pecorino Romano for a sharper flavor or nutritional yeast for a dairy-free option. Both will give a similar savory taste to the dish.

Can I make this dish ahead of time?

Absolutely! You can prepare the spinach and cheese mixture ahead of time and keep it in the fridge. Assemble the dish and bake it just before serving. This makes it a perfect option for meal prep or entertaining.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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