Mexican Chicken Spaghetti

Prep: 30 min Cook: 45 min Serves: 8 Cuisine: Mexican

A hearty Mexican-inspired chicken spaghetti casserole with spicy chili, creamy Velveeta, and tender chicken, perfect for family dinners and comfort food lovers.

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Ingredients

  • 3 lb. chicken, cooked and boned
  • 1 lb. spaghetti
  • 1 stick butter
  • 1 pkg. chili mix
  • 1 large onion
  • 1 can chopped tomatoes
  • 1 can chopped green chiles
  • 1 cup celery
  • 1 can cream of mushroom soup
  • 1 lb. Velveeta cheese

Instructions

  1. Cook and bone the chicken, then save the broth.
  2. Cook the spaghetti in the chicken broth without draining.
  3. In a large skillet, melt the butter.
  4. Add chili mix, chopped onion, chopped celery, and pepper; sauté until fragrant.
  5. Add cream of mushroom soup, chopped tomatoes, and chopped green chiles; stir to combine.
  6. Add Velveeta cheese and stir until melted and smooth.
  7. Pour the sauce over the cooked spaghetti.
  8. Add the cooked chicken and stir everything together.
  9. Transfer to a large casserole dish.
  10. Bake in a preheated oven at 300°F for 45 minutes.

Tips & Substitutions

For a creamier sauce, consider adding a splash of cream or sour cream to the cheese mixture. You can substitute the Velveeta with a mixture of cheddar and cream cheese if desired. To save time, rotisserie chicken can be used instead of cooking your own. Add more vegetables like bell peppers or corn for a nutrient boost and extra flavor.

Serving Suggestions

Serve this Mexican Chicken Spaghetti with a side of garlic bread or a fresh salad for a complete meal. It pairs beautifully with Mexican recipes like Picante Chicken-Pasta Soup for a comforting dinner. Garnish with fresh cilantro or avocado for added flavor and presentation.

Storage & Reheating

Store leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, place in a covered baking dish in a preheated oven at 350°F for about 20 minutes, or until heated through. You can also microwave individual portions, stirring occasionally for even heating.

Nutrition & Diet Analysis (per serving)

Each serving of Mexican Chicken Spaghetti contains roughly 863 calories, with 21g protein, 70g carbohydrates, and 55g fat. It is an excellent source of protein (41% of the Daily Value) and dietary fiber (22% of the Daily Value), and a good source of iron. Note that it is relatively high in sodium, at 1120mg per serving (49% of the Daily Value).

863 kcal 43% DV
Protein Fat Carbs

Macronutrients

Protein 20.7g 41% DV
Total Fat 55.2g 71% DV
Carbs 70.1g 25% DV
Fiber 6.3g 22% DV
Sugar 4.7g 9% DV

Electrolytes

Sodium 1120.2mg 49% DV
Potassium 319.2mg 7% DV
Cholesterol 157.2mg 52% DV

Vitamins & Minerals

Vitamin A 25.9mcg 3% DV
Vitamin C 8.2mg 9% DV
Vitamin D 0mcg
Calcium 92.1mg 7% DV
Iron 2.3mg 13% DV
Diet fit High-protein High-fiber
Contains Milk

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I make this dish ahead of time?

Yes, you can prepare the casserole in advance and refrigerate it before baking. Just cover it tightly with foil to keep it fresh. When ready to serve, bake as directed, adding a few extra minutes to ensure it's heated through.

Is this recipe suitable for freezing?

Absolutely! This dish freezes well. After baking, let it cool completely, then wrap it tightly in plastic wrap and foil. It can be frozen for up to 3 months. To reheat, thaw overnight in the refrigerator and bake at 350°F until warmed through.

What can I serve with Mexican Chicken Spaghetti?

This dish is versatile and can be served with a variety of sides. Consider a simple green salad, corn on the cob, or refried beans. You might also enjoy it alongside Green Chile And Chicken Enchiladas for a festive meal.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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