Pepperidge Farm Chicken Casserole

Prep: 15 min Cook: 120 min Serves: 8 Cuisine: American

A comforting chicken casserole featuring tender chicken, Swiss cheese, creamy sauce, and flavorful herb dressing, perfect for a hearty family dinner or casual gathering.

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Ingredients

  • 4 chicken breasts, halved and skinned
  • 8 slices Swiss cheese
  • 1 can cream of chicken soup
  • 1/2 can water
  • 3/4 to 1 cup Pepperidge Farm herb dressing mix
  • 1/2 cup melted margarine

Instructions

  1. Put the chicken breasts in a 9 x 13-inch pan.
  2. Place one slice of Swiss cheese on top of each piece of chicken.
  3. Mix the cream of chicken soup with water and pour over the chicken.
  4. Sprinkle the Pepperidge Farm herb dressing mix on top of the casserole.
  5. Drizzle the melted margarine over the top.
  6. Bake at 325°F (163°C) for 2 hours.

Tips & Substitutions

For a creamier texture, consider adding a splash of milk to the cream of chicken soup before pouring it over the chicken. If Swiss cheese isn't available, Gruyère or provolone can be good substitutes. To enhance the flavor, you can add some garlic powder or fresh herbs like thyme or parsley to the dressing mix. This dish is similar to other comforting chicken recipes like Coach Taylor's Favorite Chicken Casserole.

Serving Suggestions

This casserole is best served warm and pairs beautifully with a light side salad or steamed vegetables, such as green beans or broccoli. For a heartier meal, consider serving it alongside California Potatoes. A side of cranberry sauce can also add a nice contrast to the savory flavors of the dish.

Storage & Reheating

Leftovers can be stored in an airtight container in the refrigerator for up to 3 days. To reheat, preheat your oven to 350°F (175°C) and cover the casserole with foil to retain moisture. Bake for about 20-30 minutes, or until heated thoroughly. You can also use the microwave for quicker reheating, but the oven will help maintain texture.

Nutrition & Diet Analysis (per serving)

Each serving of Pepperidge Farm Chicken Casserole contains roughly 352 calories, with 20g protein, 4g carbohydrates, and 28g fat. It is an excellent source of protein (40% of the Daily Value) and calcium (35% of the Daily Value), and a good source of vitamin A. Note that it is relatively high in sodium, at 522mg per serving (23% of the Daily Value).

352 kcal 18% DV
Protein Fat Carbs

Macronutrients

Protein 19.9g 40% DV
Total Fat 28.3g 36% DV
Carbs 4.4g 2% DV
Fiber 0g
Sugar 0.3g 1% DV

Electrolytes

Sodium 522.1mg 23% DV
Potassium 117.2mg 2% DV
Cholesterol 66.5mg 22% DV

Vitamins & Minerals

Vitamin A 171.5mcg 19% DV
Vitamin C 0.1mg
Vitamin D 0.1mcg 1% DV
Calcium 457.5mg 35% DV
Iron 0.8mg 4% DV
Diet fit Keto-friendly Under 400 cal
Contains Milk

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I use frozen chicken breasts for this recipe?

Yes, you can use frozen chicken breasts, but it's best to thaw them first for even cooking. If you are short on time, you can cook them straight from frozen, but increase the baking time to ensure they reach a safe internal temperature.

What can I use instead of cream of chicken soup?

If you don't have cream of chicken soup, you can use homemade white sauce or substitute with cream of mushroom soup for a different flavor profile. Alternatively, a mixture of sour cream and chicken broth can also work as a substitute.

Is it possible to make this dish ahead of time?

Absolutely! You can assemble the casserole a day in advance and store it in the refrigerator until you're ready to bake it. Just remember to adjust the baking time if you're cooking it straight from the fridge, as it may need a little extra time to heat through.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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