"Pepperidge Farm" Squash Casserole

Prep: 20 min Cook: 30 min Serves: 8 Cuisine: American

A creamy, cheesy squash casserole featuring tender cooked squash, savory stuffing, and melted cheese, perfect for family dinners or holiday gatherings with comforting flavors.

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Ingredients

  • 4 cups squash, sliced and cooked
  • 1 chopped onion
  • 3/4 cup water
  • 1 can cream of chicken soup
  • 8 ounces sour cream
  • salt and pepper to taste
  • Pepperidge Farm stuffing mix
  • 3/4 cup shredded Cheddar cheese

Instructions

  1. Mix cooked squash, margarine, and chopped onion in a bowl.
  2. In a separate bowl, combine water, cream of chicken soup, sour cream, salt, and pepper.
  3. Pour the soup mixture into the squash mixture and stir well.
  4. Layer the mixture in a 3-quart casserole dish, starting with the squash mixture, then adding a layer of Pepperidge Farm stuffing mix, and repeating, ending with stuffing mix on top.
  5. Sprinkle shredded Cheddar cheese over the top.
  6. Bake at 350°F for 30 minutes until bubbly and golden.

Tips & Substitutions

For optimal flavor, consider adding a pinch of garlic powder or fresh herbs like thyme to the squash mixture. If you don't have cream of chicken soup, a homemade version can be made using chicken broth, milk, and a thickener. You can also substitute Greek yogurt for sour cream for a healthier twist. This dish can easily be adjusted for different vegetables, such as zucchini or mushrooms.

Serving Suggestions

This squash casserole pairs beautifully with a simple green salad or steamed vegetables for a complete meal. For a heartier option, serve alongside roasted chicken or grilled sausages. It can also be a delightful side dish for holiday gatherings or potlucks, complementing other favorites like Lattice Top Chicken Pie.

Storage & Reheating

Store any leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, preheat your oven to 350°F and cover the casserole with foil to prevent drying out. Bake for about 20 minutes, or until heated through. You can also microwave individual portions for a quicker option.

Nutrition & Diet Analysis (per serving)

Each serving of "Pepperidge Farm" Squash Casserole contains roughly 445 calories, with 16g protein, 26g carbohydrates, and 31g fat. It is an excellent source of protein (33% of the Daily Value), calcium (31% of the Daily Value), and vitamin A (28% of the Daily Value), and a good source of iron. Note that it is relatively high in sodium, at 2275mg per serving (99% of the Daily Value).

445 kcal 22% DV
Protein Fat Carbs

Macronutrients

Protein 16.5g 33% DV
Total Fat 30.9g 40% DV
Carbs 26.1g 9% DV
Fiber 0.8g 3% DV
Sugar 2.8g 6% DV

Electrolytes

Sodium 2275.4mg 99% DV
Potassium 163.2mg 3% DV
Cholesterol 60.2mg 20% DV

Vitamins & Minerals

Vitamin A 254.9mcg 28% DV
Vitamin C 0.6mg 1% DV
Vitamin D 0.3mcg 2% DV
Calcium 403.6mg 31% DV
Iron 1.9mg 11% DV
Contains Milk

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I use frozen squash for this recipe?

Yes, frozen squash can be used, but be sure to thaw and drain any excess moisture before cooking. This will help maintain the texture of the casserole. Just remember that cooking times may vary slightly, so check for doneness before serving.

Can I make this casserole ahead of time?

Absolutely! You can prepare the casserole up to a day in advance. Simply assemble it, cover tightly, and refrigerate. When ready to bake, allow it to come to room temperature before placing it in the oven, and adjust the baking time as needed.

What can I substitute for the Pepperidge Farm stuffing mix?

If you prefer a homemade option, you can use seasoned bread cubes or croutons mixed with your favorite herbs and spices. Alternatively, for a gluten-free version, look for gluten-free stuffing mixes available in stores, which can work just as well in this dish.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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