Rotel Chicken Spaghetti Casserole

Prep: 20 min Cook: 30 min Serves: 6 Cuisine: American

A hearty chicken spaghetti casserole featuring tender chicken, melting Velveeta, and flavorful Ro-Tel tomatoes, perfect for comforting family dinners or gatherings.

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Ingredients

  • 6 chicken breasts
  • 2 large onions, diced
  • 1/2 lb Velveeta cheese, diced
  • 2 cans Ro-Tel tomatoes
  • 1 can cream of mushroom soup
  • 1 bell pepper, diced
  • 14 oz spaghetti

Instructions

  1. Boil chicken breasts with 1/2 cup of diced onions until cooked.
  2. Remove chicken from broth and set aside to cool slightly.
  3. Save the broth for cooking the spaghetti.
  4. Remove the skin from the chicken and cut into bite-sized pieces.
  5. Add more water to the broth and cook the spaghetti until al dente.
  6. Meanwhile, mix remaining diced onions, Ro-Tel tomatoes, cream of mushroom soup, diced bell pepper, and Velveeta cheese in a pot.
  7. Heat the mixture on low heat until the cheese melts, stirring occasionally to prevent burning.
  8. Drain the cooked spaghetti and stir it into the tomato mixture.
  9. Pour the combined mixture into a lightly greased baking dish.
  10. Bake at 350°F (175°C) for 30 minutes until bubbly and heated through.

Tips & Substitutions

For a creamier texture, you can substitute cream cheese for half of the Velveeta. Feel free to add additional vegetables like mushrooms or zucchini for extra nutrition. If you're in a hurry, pre-cooked rotisserie chicken can be used instead of boiling the chicken breasts. This recipe is a great way to use leftover chicken from a previous meal.

Serving Suggestions

Serve the casserole with a fresh green salad or garlic bread for a complete meal. It pairs beautifully with Easy, Quick, Delicious Soup for a comforting dinner. You can also top the casserole with some fresh chopped cilantro or parsley for added flavor and freshness just before serving.

Storage & Reheating

Store any leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, place the casserole in the oven at 350°F (175°C) until warmed through, about 15-20 minutes. You can also microwave individual portions for 2-3 minutes, stirring halfway through for even heating.

Nutrition & Diet Analysis (per serving)

Each serving of Rotel Chicken Spaghetti Casserole contains roughly 367 calories, with 21g protein, 49g carbohydrates, and 10g fat. It is an excellent source of vitamin C (190% of the Daily Value), protein (43% of the Daily Value), and vitamin A (25% of the Daily Value), and a good source of dietary fiber and iron. At about 367 calories per serving, it is a lighter, protein-rich choice.

367 kcal 18% DV
Protein Fat Carbs

Macronutrients

Protein 21.4g 43% DV
Total Fat 10g 13% DV
Carbs 48.8g 18% DV
Fiber 5.3g 19% DV
Sugar 8.5g 17% DV

Electrolytes

Sodium 267.8mg 12% DV
Potassium 488.8mg 10% DV
Cholesterol 29.1mg 10% DV

Vitamins & Minerals

Vitamin A 223.1mcg 25% DV
Vitamin C 170.8mg 100% DV
Vitamin D 0.2mcg 1% DV
Calcium 98.7mg 8% DV
Iron 1.9mg 11% DV
Diet fit High-protein High-fiber Under 400 cal Low-fat
Contains Milk

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

What can I substitute for Ro-Tel tomatoes?

If you don't have Ro-Tel tomatoes, you can use regular diced tomatoes mixed with a bit of diced green chilies to mimic the flavor. Alternatively, any canned tomatoes with spices can work, though the taste may vary slightly.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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