San Antonio Casserole
A hearty layered casserole with ground beef, green chilies, and cheese, perfect for comforting family dinners and easy to prepare ahead of time.
Ingredients
Instructions
- In a large skillet, brown beef and onion in oil.
- In a large mixing bowl, combine cream of mushroom soup and milk.
- Stir until well blended; stir in diced green chilies.
- Quarter the corn tortillas and layer the bottom of a 13 x 9-inch baking pan.
- Spread with half of the meat mixture and half of the soup mixture.
- Top with half of the grated Cheddar cheese.
- Repeat layers with remaining tortillas, meat mixture, soup mixture, and cheese.
- Bake at 350°F for 30 minutes.
Tips & Substitutions
For a healthier twist, consider using ground turkey or chicken instead of lean ground round. You can substitute the cream of mushroom soup with a homemade version or a low-fat option for a lighter dish. If you prefer a spicier casserole, add diced jalapeños or use spicy diced green chilies. Make sure to cut the corn tortillas into quarters for easier layering.
Serving Suggestions
This San Antonio Casserole is perfect as a hearty main dish and pairs beautifully with a fresh side salad or some Mexican Appetizer Rolls for a complete meal. For a more festive occasion, consider serving it with a side of guacamole and tortilla chips. It also goes well with Bud'S Mexican Corn Bread for a comforting and filling dinner.
Storage & Reheating
Store any leftovers in an airtight container in the refrigerator for up to 3-4 days. To reheat, cover the casserole with foil and warm it in a preheated oven at 350°F for about 20-25 minutes, or until heated through. You can also microwave individual portions for convenience.
Nutrition & Diet Analysis (per serving)
Each serving of San Antonio Casserole contains roughly 2054 calories, with 42g protein, 301g carbohydrates, and 77g fat. It is an excellent source of calcium (132% of the Daily Value), iron (125% of the Daily Value), and vitamin A (86% of the Daily Value). Note that it is relatively high in sodium, at 2151mg per serving (94% of the Daily Value).
Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.
* % Daily Values based on a 2,000 calorie diet (FDA 2020).
Frequently Asked Questions
Can I make this casserole ahead of time?
Yes, you can prepare the casserole a day in advance and refrigerate it before baking. Just cover it tightly with plastic wrap or foil. When you're ready to bake, remove the cover and allow it to come to room temperature for about 30 minutes before placing it in the oven.
What can I use instead of corn tortillas?
If you're looking for a gluten-free option, you can use corn or gluten-free flour tortillas. Alternatively, for a low-carb version, try using zucchini slices or eggplant as layers instead of tortillas. Just make sure to adjust the baking time accordingly.
Can I freeze the casserole?
Yes, you can freeze the assembled casserole before baking. Wrap it tightly with aluminum foil or plastic wrap to prevent freezer burn. When ready to eat, thaw it in the refrigerator overnight and bake as directed, adding a few extra minutes if needed.
Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).