Bisquick Lasagna Squares

Prep: 15 min Cook: 35 min Serves: 6 Cuisine: American

Creamy and cheesy, Bisquick Lasagna Squares combine the flavors of classic lasagna with a soft, biscuit-like topping. Perfect for family dinners or casual gatherings, this dish offers a comforting blend of meat, cheese, and herbs in every bite, baked to golden perfection.

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Ingredients

  • 1/2 cup cottage cheese
  • 1/4 cup grated Parmesan cheese
  • 1 pound hamburger, cooked and drained
  • 1 teaspoon oregano
  • 1/2 teaspoon basil
  • 1 (6 oz.) can tomato paste
  • 2 cups shredded Mozzarella cheese
  • 1 cup milk
  • 2 eggs
  • 2/3 cup Bisquick
  • salt and pepper

Instructions

  1. Preheat oven to 400°F (200°C).
  2. Grease an 8 x 8 x 2-inch pan.
  3. Spread cottage cheese on the bottom of the prepared pan and sprinkle with Parmesan cheese.
  4. Mix cooked hamburger, oregano, basil, tomato paste, and 1 cup of shredded Mozzarella cheese.
  5. Spoon the meat mixture into the prepared pan over the cheese layer.
  6. In a bowl, beat eggs, milk, Bisquick, salt, and pepper until smooth.
  7. Pour the batter evenly over the meat layer.
  8. Bake in the preheated oven until a knife inserted comes out clean, about 30 to 35 minutes.
  9. Sprinkle the remaining 1 cup of Mozzarella cheese on top and bake for an additional 5 minutes until cheese melts.

Tips & Substitutions

For a creamier texture, consider mixing in ricotta cheese with the cottage cheese. If you're looking for a lighter option, substitute ground turkey for the hamburger. You can also add vegetables like spinach or zucchini for added nutrition. Ensure to season the layers with salt and pepper to enhance the flavor, just like you would in classic American recipes.

Serving Suggestions

Serve the Bisquick Lasagna Squares with a side of garlic bread or a fresh salad, like Broccoli Cashew Salad, to complement the flavors. This dish also pairs beautifully with Uncle Terry's Too-Good Tomato Gravy for added richness. Perfect for potlucks or family dinners, it’s sure to please everyone.

Storage & Reheating

Store leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, place in the microwave for a few minutes or bake in the oven at 350°F (175°C) until warmed through. Cover with foil to prevent the cheese from over-browning during reheating.

Nutrition & Diet Analysis (per serving)

Each serving of Bisquick Lasagna Squares contains roughly 553 calories, with 20g protein, 100g carbohydrates, and 11g fat. It is an excellent source of iron (55% of the Daily Value), calcium (44% of the Daily Value), and protein (40% of the Daily Value). Note that it is relatively high in sodium, at 872mg per serving (38% of the Daily Value).

553 kcal 28% DV
Protein Fat Carbs

Macronutrients

Protein 20.2g 40% DV
Total Fat 11.1g 14% DV
Carbs 99.7g 36% DV
Fiber 8.4g 30% DV
Sugar 10.7g 21% DV

Electrolytes

Sodium 872.4mg 38% DV
Potassium 1574.6mg 34% DV
Cholesterol 220.1mg 73% DV

Vitamins & Minerals

Vitamin A 234.6mcg 26% DV
Vitamin C 24.5mg 27% DV
Vitamin D 0mcg
Calcium 567.9mg 44% DV
Iron 9.9mg 55% DV
Diet fit High-protein High-fiber Low-fat
Contains Milk Egg

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I make this recipe ahead of time?

Yes, you can prepare the layers in advance and assemble the dish. Cover and refrigerate until ready to bake. This can save time during busy weeknights, allowing the flavors to meld together beautifully.

What can I use instead of Bisquick?

If you don't have Bisquick on hand, you can make a substitute by mixing 1 cup of all-purpose flour with 1 1/2 teaspoons of baking powder and a pinch of salt. This will provide a similar texture for the recipe.

Can I freeze Bisquick Lasagna Squares?

Absolutely! Freeze the baked and cooled squares in an airtight container or freezer bag for up to 3 months. Thaw in the refrigerator overnight before reheating in the oven or microwave.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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