Bow Tie Casserole

Prep: 20 min Cook: 35 min Serves: 8 Cuisine: American

A hearty bow tie casserole layered with seasoned ground beef, pepperoni, melted cheeses, and rich spaghetti sauce, perfect for family dinners or casual gatherings.

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Ingredients

  • 2 lb. bow tie noodles
  • 1 1/2 to 2 lb. ground chuck
  • 1 lb. pepperoni slices
  • 2 qt. spaghetti sauce
  • 1 lb. Provolone cheese
  • 16 slices Mozzarella cheese

Instructions

  1. Cook the bow tie noodles and drain.
  2. Divide the cooked noodles evenly into two 9 x 13-inch pans.
  3. Brown the ground chuck and drain excess fat.
  4. Cut the pepperoni into half-moon shapes and add to the spaghetti sauce. Simmer the sauce.
  5. Grate the Provolone cheese and add it to the sauce.
  6. Stir the browned ground chuck into the sauce.
  7. Pour the sauce mixture over the noodles in each pan.
  8. Top each casserole with slices of Mozzarella cheese (8 slices per pan).
  9. Bake at 350°F until the cheese is melted and bubbly.

Tips & Substitutions

For a lighter version, you can substitute ground turkey for ground chuck and use whole grain bow tie noodles. If you prefer a spicier kick, add sliced jalapeños to the sauce. To save time, use pre-made spaghetti sauce. Make sure to drain the noodles well to avoid a soggy casserole. This dish pairs beautifully with salads or garlic bread.

Serving Suggestions

Serve the Bow Tie Casserole with a side of mixed greens or a Caesar salad for a complete meal. Garlic bread or cheesy breadsticks complement the dish well, adding a nice crunch. For a comforting dessert, consider serving Gene Autry Peanut Butter Pie for a delightful finish to your dinner.

Storage & Reheating

Leftovers can be stored in an airtight container in the refrigerator for up to 4 days. To reheat, preheat your oven to 350°F, cover the casserole with foil, and bake for about 20 minutes or until heated through. You can also reheat individual portions in the microwave for 1-2 minutes, checking for warmth.

Nutrition & Diet Analysis (per serving)

Each serving of Bow Tie Casserole contains roughly 1158 calories, with 69g protein, 112g carbohydrates, and 48g fat. It is an excellent source of protein (137% of the Daily Value), iron (50% of the Daily Value), and calcium (47% of the Daily Value). Note that it is relatively high in sodium, at 954mg per serving (41% of the Daily Value).

1158 kcal 58% DV
Protein Fat Carbs

Macronutrients

Protein 68.7g 100% DV
Total Fat 47.7g 61% DV
Carbs 112.2g 41% DV
Fiber 1.5g 5% DV
Sugar 2.2g 4% DV

Electrolytes

Sodium 954.1mg 41% DV
Potassium 1011.6mg 22% DV
Cholesterol 227.2mg 76% DV

Vitamins & Minerals

Vitamin A 184.5mcg 20% DV
Vitamin C 0.4mg
Vitamin D 0.7mcg 3% DV
Calcium 604.7mg 47% DV
Iron 9mg 50% DV
Diet fit High-protein
Contains Milk Wheat/Gluten

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I make this casserole ahead of time?

Yes, you can prepare the casserole a day in advance. Assemble it in the pan, cover it tightly with plastic wrap or foil, and refrigerate. When ready to bake, remove from the fridge and bake as directed, adding a few extra minutes to the cooking time if it's cold from the fridge.

What can I use instead of Provolone cheese?

If you can't find Provolone cheese, you can substitute it with mozzarella or a mild cheddar cheese. These cheeses will melt well and provide a similar creamy texture to the casserole. Just ensure to use a cheese that melts nicely for the best results.

Is it possible to freeze Bow Tie Casserole?

Absolutely! You can freeze the casserole either before or after baking. If freezing before baking, wrap it tightly in foil and store it in the freezer for up to 3 months. To bake from frozen, add an additional 30-40 minutes to the baking time. If you freeze leftovers after baking, store them in an airtight container for up to 2 months.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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