Cheeseburger Or Hamburger Casserole

Prep: 10 min Cook: 40 min Serves: 4 Cuisine: American

A comforting cheeseburger casserole with savory beef, melted cheese, and biscuit topping, perfect for quick weeknight dinners or casual gatherings with bold flavors.

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Ingredients

  • 1 lb. lean ground beef
  • 1/2 tsp. salt
  • 1/2 tsp. pepper
  • 1/4 cup onion, chopped
  • 1/4 cup green bell pepper, chopped
  • 1 (8 oz.) can tomato sauce
  • 4 slices processed American cheese
  • 1 (6 oz.) can refrigerated biscuits

Instructions

  1. Brown ground beef in a large skillet over medium heat, stirring until it crumbles; drain.
  2. Return beef to skillet.
  3. Stir in salt, pepper, chopped onion, and chopped green bell pepper; cook for 1 minute.
  4. Add tomato sauce; reduce heat, and simmer for 15 minutes.
  5. Spoon the mixture into an 8-inch square baking dish; top with slices of processed American cheese, if desired.
  6. Flatten biscuits into 3 1/2 inch circles, and place on top of the casserole, directly over the cheese slices if used.
  7. Bake at 350°F for 20 to 25 minutes or until biscuits are browned.

Tips & Substitutions

For added flavor, consider using garlic powder or Worcestershire sauce in the beef mixture. If you prefer a healthier option, swap the processed American cheese for a lower-fat cheese or a blend of shredded cheeses. You can also substitute the ground beef with ground turkey or chicken for a lighter version, similar to other American recipes. For a vegetarian twist, try using lentils or a meat substitute.

Serving Suggestions

Serve this cheeseburger casserole with a fresh side salad or steamed vegetables for a balanced meal. You can also pair it with pickles or coleslaw for a crunchy contrast. This dish is great for a family dinner and is reminiscent of easy comfort foods like Easy Sloppy Joes, making it a hit with both kids and adults.

Storage & Reheating

Store leftovers in an airtight container in the refrigerator for up to 3 days. When reheating, cover the casserole with foil to prevent the biscuits from over-browning. You can reheat it in the oven at 350°F until warmed through, or microwave individual portions for about 2-3 minutes, checking for doneness.

Nutrition & Diet Analysis (per serving)

Each serving of Cheeseburger Or Hamburger Casserole contains roughly 262 calories, with 11g protein, 34g carbohydrates, and 9g fat. It is an excellent source of protein (21% of the Daily Value), and a good source of iron and calcium. Note that it is relatively high in sodium, at 2461mg per serving (107% of the Daily Value).

262 kcal 13% DV
Protein Fat Carbs

Macronutrients

Protein 10.7g 21% DV
Total Fat 9.5g 12% DV
Carbs 33.9g 12% DV
Fiber 0.7g 3% DV
Sugar 1.8g 4% DV

Electrolytes

Sodium 2460.6mg 100% DV
Potassium 421.8mg 9% DV
Cholesterol 15.9mg 5% DV

Vitamins & Minerals

Vitamin A 14.9mcg 2% DV
Vitamin C 3mg 3% DV
Vitamin D 0mcg
Calcium 124.3mg 10% DV
Iron 2.4mg 13% DV
Diet fit Under 400 cal
Contains Milk

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I make this casserole ahead of time?

Yes, you can prepare the beef mixture and assemble the casserole a day in advance. Just cover it tightly and refrigerate. When ready to bake, add the biscuits and adjust the baking time as needed. This makes it a convenient option for busy weeknights.

What can I use instead of biscuits?

If you don’t have biscuits on hand, you can use puff pastry or even a cornbread topping. You could also try mashed potatoes for a comforting variation. Each option will give a different texture but will still complement the flavors of the beef mixture.

How can I spice this up?

For a spicier version, add diced jalapeños or a dash of hot sauce to the beef mixture. You can also sprinkle red pepper flakes over the top before baking. This will enhance the flavor profile and make it more appealing for those who enjoy a bit of heat.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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