Mexican Cheese Casserole

Prep: 15 min Cook: 30 min Serves: 8 Cuisine: Mexican

A flavorful Mexican cheese casserole featuring seasoned ground beef, melted cheeses, and a spicy enchilada twist, perfect for a hearty family meal or casual gathering.

Be the first to rate this recipe

Ingredients

  • 1 lb ground beef
  • 2 cans cream of mushroom soup
  • 1 small can green chiles, chopped
  • 1/4 cup chopped onion
  • 1 can enchilada sauce
  • 1/2 lb Monterey Jack cheese, grated
  • 1/2 lb Cheddar cheese, grated
  • 10 to 12 flour tortillas

Instructions

  1. Brown the ground beef and drain off the fat.
  2. In a large bowl, combine the cream of mushroom soup, enchilada sauce, chopped green chiles, and chopped onion.
  3. Add the cooked meat and half of each grated cheese to the mixture, then stir to combine.
  4. Place about 2 tablespoons of the mixture onto each flour tortilla and roll them up.
  5. Arrange the filled tortillas close together in a large baking dish.
  6. Spread any remaining meat mixture over the rolled tortillas.
  7. Sprinkle the remaining half of each cheese over the top.
  8. Bake at 350°F (175°C) for 15 to 30 minutes, or until the cheese melts and the rolls are hot through.

Tips & Substitutions

For a spicier kick, consider adding jalapeños or using spicy enchilada sauce. If ground beef isn't available, ground turkey or chicken can be a healthier substitute. You can also use corn tortillas for a gluten-free option. Make sure to warm the tortillas slightly before rolling to prevent tearing. This dish is a fantastic way to incorporate leftover ingredients from other Mexican recipes.

Serving Suggestions

Serve the Mexican Cheese Casserole with a fresh side salad or Mexican rice for a complete meal. It pairs wonderfully with guacamole and sour cream for added creaminess. For an indulgent touch, serve alongside The Mountain Dip(Nacho Style) for a fun appetizer. This casserole is perfect for potlucks or family gatherings, making it a versatile Mexican Party Dish.

Storage & Reheating

Store any leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, cover the casserole with foil and bake at 350°F (175°C) for about 20 minutes, or until heated through. For a quicker option, you can microwave individual portions on medium power until warm.

Nutrition & Diet Analysis (per serving)

Each serving of Mexican Cheese Casserole contains roughly 844 calories, with 36g protein, 76g carbohydrates, and 44g fat. It is an excellent source of protein (71% of the Daily Value) and iron (37% of the Daily Value), and a good source of dietary fiber and calcium. Note that it is relatively high in sodium, at 1053mg per serving (46% of the Daily Value).

844 kcal 42% DV
Protein Fat Carbs

Macronutrients

Protein 35.5g 71% DV
Total Fat 43.5g 56% DV
Carbs 75.6g 27% DV
Fiber 4.6g 16% DV
Sugar 3.9g 8% DV

Electrolytes

Sodium 1052.9mg 46% DV
Potassium 587.6mg 13% DV
Cholesterol 99mg 33% DV

Vitamins & Minerals

Vitamin A 49.9mcg 6% DV
Vitamin C 0.9mg 1% DV
Vitamin D 0.2mcg 1% DV
Calcium 176.8mg 14% DV
Iron 6.6mg 37% DV
Diet fit High-protein
Contains Milk Wheat/Gluten

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I make this casserole ahead of time?

Yes, you can prepare the casserole up to the baking step, cover it tightly, and refrigerate for up to 24 hours. When ready to bake, allow it to come to room temperature for about 30 minutes before placing it in the oven to ensure even cooking.

Can I freeze the Mexican Cheese Casserole?

Absolutely! To freeze, assemble the casserole but do not bake it. Wrap tightly with plastic wrap and then aluminum foil, and it can be frozen for up to 3 months. When ready to enjoy, thaw in the refrigerator overnight and bake as directed.

What can I substitute for cream of mushroom soup?

If you're looking for a substitute for cream of mushroom soup, you can use cream of chicken soup or a homemade white sauce as alternatives. For a vegetarian option, consider using a can of cream of celery soup or a blended mixture of sautéed mushrooms and cream for similar flavor and texture.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

Mexican recipes → Beef recipes → Dairy recipes → All recipes →