Three Cheese Chicken Lasagna

Prep: 20 min Cook: 45 min Serves: 8 Cuisine: American

A creamy, cheesy chicken lasagna layered with tender noodles, seasoned vegetables, and a rich blend of cheeses including American, Parmesan, and cottage cheese. This comforting dish is perfect for family dinners or entertaining guests, offering a hearty and flavorful twist on traditional lasagna with a delicious chicken addition.

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Ingredients

  • 8 oz. lasagna noodles
  • 1/2 cup chopped onion
  • 1/2 cup chopped green pepper
  • 3 tablespoons butter
  • 1 can cream of chicken soup
  • 6 oz. can mushrooms, drained
  • 1/2 cup chopped pimento
  • 1/3 cup milk
  • 1/2 teaspoon dried basil
  • 1 1/2 cups cottage cheese
  • 2 cups diced chicken
  • 2 cups shredded American cheese
  • 1/2 cup grated Parmesan cheese

Instructions

  1. Cook the lasagna noodles until tender and drain.
  2. Sauté chopped onion and green pepper in butter until tender.
  3. Stir in cream of chicken soup, drained mushrooms, chopped pimento, milk, and dried basil to make the sauce.
  4. Lay half of the cooked noodles in a 13 x 9-inch baking pan.
  5. Spread half of the sauce mixture over the noodles.
  6. Add half of the cottage cheese, diced chicken, shredded American cheese, and grated Parmesan cheese on top of the sauce.
  7. Repeat the layering with remaining noodles, sauce, cheeses, and chicken, except for the last layer of cheeses.
  8. Bake at 350°F for 45 minutes.
  9. Sprinkle remaining cheeses on top.
  10. Bake a few minutes more until cheese is melted and bubbly.

Tips & Substitutions

For a creamier texture, consider adding a layer of ricotta cheese or using a mix of cheeses like mozzarella for added stretchiness. You can substitute the diced chicken with shredded rotisserie chicken for convenience. Fresh basil can replace dried basil for a fresher flavor. If you're short on time, try using no-boil lasagna noodles to simplify the cooking process.

Serving Suggestions

This three cheese chicken lasagna pairs beautifully with a simple side salad or garlic bread for a complete meal. You can also serve it alongside steamed vegetables for a nutritious touch. Consider offering a light red wine or sparkling water to complement the richness of the dish.

Storage & Reheating

Store leftovers in an airtight container in the refrigerator for up to 3-4 days. To reheat, cover with foil and bake at 350°F for about 20-25 minutes, or until heated through. You can also microwave individual portions, but be sure to cover them to retain moisture.

Nutrition & Diet Analysis (per serving)

Each serving of Three Cheese Chicken Lasagna contains roughly 698 calories, with 11g protein, 17g carbohydrates, and 66g fat. It is an excellent source of vitamin C (71% of the Daily Value), protein (21% of the Daily Value), and vitamin D (20% of the Daily Value), and a good source of calcium and iron. Note that it is relatively high in sodium, at 535mg per serving (23% of the Daily Value).

698 kcal 35% DV
Protein Fat Carbs

Macronutrients

Protein 10.5g 21% DV
Total Fat 65.9g 84% DV
Carbs 16.8g 6% DV
Fiber 2.1g 7% DV
Sugar 4.1g 8% DV

Electrolytes

Sodium 535.1mg 23% DV
Potassium 341.3mg 7% DV
Cholesterol 191.7mg 64% DV

Vitamins & Minerals

Vitamin A 77.2mcg 9% DV
Vitamin C 63.5mg 71% DV
Vitamin D 4mcg 20% DV
Calcium 159.6mg 12% DV
Iron 1.7mg 10% DV
Diet fit Low-carb
Contains Milk Wheat/Gluten

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I make this lasagna ahead of time?

Yes, you can assemble the lasagna a day in advance. Just cover it tightly with plastic wrap or aluminum foil and refrigerate. When ready to bake, remove the cover and allow it to sit at room temperature for about 30 minutes before baking as directed.

Can I freeze this lasagna?

Absolutely! You can freeze the assembled lasagna before baking. Wrap it tightly in plastic wrap and then in aluminum foil. It will keep well for up to 3 months. When ready to bake, thaw in the refrigerator overnight and then bake as instructed.

What can I substitute for cream of chicken soup?

If you prefer a homemade option, you can use a white sauce made from butter, flour, and chicken broth. Alternatively, a store-bought cream of mushroom soup can also work well for a slightly different flavor while keeping the dish creamy.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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