Tortilla Meat Loaf

Prep: 15 min Cook: 55 min Serves: 8 Cuisine: Mexican

A flavorful meatloaf with a Mexican twist, featuring spicy picante sauce, crunchy tortilla chips, and melted cheeses—perfect for a hearty, satisfying meal with bold flavors.

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Ingredients

  • 1 1/2 lb. lean ground beef
  • 1 1/3 c. picante sauce
  • 1/2 c. quick oats
  • 1/2 c. plus 2 Tbsp. finely crushed tortilla chips
  • 3/4 c. onions, chopped
  • 1 egg
  • 2 tsp. ground cumin
  • 1 tsp. garlic powder
  • 3/4 tsp. salt
  • 1/3 c. shredded sharp cheese
  • 1/2 c. shredded Monterey cheese

Instructions

  1. In a large bowl, combine ground beef, 1 cup picante sauce, oats, 1/2 cup crushed tortilla chips, chopped onions, egg, ground cumin, garlic powder, and salt. Mix well.
  2. Press the mixture firmly into an 8-inch baking dish.
  3. Bake at 350°F (175°C) for 50 to 55 minutes.

Tips & Substitutions

For a twist on flavor, consider using ground turkey or chicken instead of beef. You can also substitute the quick oats with breadcrumbs for a different texture. If you prefer a spicier flavor, try adding diced jalapeños or using a hotter picante sauce. Make sure to pack the meat mixture tightly in the baking dish to ensure it holds together during baking.

Serving Suggestions

Serve this Tortilla Meat Loaf with a side of Mexican-style rice or a fresh garden salad for a complete meal. It pairs beautifully with Easy Taco Bake for a fun dinner theme. Top with additional picante sauce or salsa and a sprinkle of fresh cilantro for extra flavor. Consider adding guacamole or sour cream on the side for a creamy contrast.

Storage & Reheating

Store any leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, place individual portions in the microwave for 1-2 minutes or until heated through. Alternatively, you can reheat in the oven at 350°F (175°C) for about 15-20 minutes, covered with foil to retain moisture.

Nutrition & Diet Analysis (per serving)

Each serving of Tortilla Meat Loaf contains roughly 680 calories, with 24g protein, 102g carbohydrates, and 23g fat. It is an excellent source of iron (163% of the Daily Value), calcium (58% of the Daily Value), and protein (48% of the Daily Value), and a good source of vitamin A. Note that it is relatively high in sodium, at 1407mg per serving (61% of the Daily Value).

680 kcal 34% DV
Protein Fat Carbs

Macronutrients

Protein 23.8g 48% DV
Total Fat 23.4g 30% DV
Carbs 102.5g 37% DV
Fiber 6.1g 22% DV
Sugar 1.6g 3% DV

Electrolytes

Sodium 1407mg 61% DV
Potassium 1294.6mg 28% DV
Cholesterol 239.7mg 80% DV

Vitamins & Minerals

Vitamin A 114.7mcg 13% DV
Vitamin C 3.6mg 4% DV
Vitamin D 0.1mcg 1% DV
Calcium 748.1mg 58% DV
Iron 29.4mg 100% DV
Diet fit High-protein High-fiber
Contains Milk Egg

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I use a different type of meat for this recipe?

Yes, you can substitute lean ground turkey or chicken for the ground beef if you prefer a lighter option. Just be aware that cooking times may vary slightly, so check for doneness accordingly.

How can I make this recipe gluten-free?

To make this Tortilla Meat Loaf gluten-free, use certified gluten-free tortilla chips and oats. Ensure that your picante sauce is also gluten-free, as some brands may contain gluten in their ingredients.

Can I freeze the meatloaf for later use?

Absolutely! After baking, allow the meatloaf to cool completely, then wrap it tightly in plastic wrap and aluminum foil or place it in a freezer-safe container. It can be frozen for up to 3 months. To reheat, thaw in the refrigerator overnight and bake at 350°F (175°C) until heated through.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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