Tuna Cheese Biscuit Casserole

Prep: 10 min Cook: 30 min Serves: 4 Cuisine: American

A creamy tuna and cheese casserole with flaky biscuits, perfect for a comforting family dinner with savory flavors and easy preparation.

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Ingredients

  • 1 can tuna
  • 1 can Cheddar cheese soup
  • 1 cup milk
  • 2 tablespoons minced onion
  • 1 can refrigerated biscuits

Instructions

  1. Place the refrigerated biscuits in an ungreased 9-inch square pan.
  2. In a bowl, combine the tuna, Cheddar cheese soup, milk, and minced onion.
  3. Pour the mixture over the biscuits in the pan.
  4. Bake in a 400°F oven for 25 to 30 minutes until hot and bubbly.

Tips & Substitutions

For added flavor, consider using a flavored tuna or adding spices like garlic powder or paprika. You can substitute the Cheddar cheese soup with cream of mushroom soup for a different taste. If you're looking for a lighter version, opt for low-fat milk and reduced-fat biscuits. This dish can be enhanced with vegetables such as peas or corn, which pair beautifully with the tuna.

Serving Suggestions

Serve the Tuna Cheese Biscuit Casserole with a crisp green salad or steamed vegetables to balance the richness of the dish. For a heartier meal, pair it with baked potatoes or a side of rice. This comforting casserole is perfect for a family dinner and can also be enjoyed alongside other seafood recipes for a delightful spread.

Storage & Reheating

Store any leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, place servings in a microwave-safe dish and warm in the microwave until heated through, or reheat in the oven at 350°F until bubbly. This casserole is best enjoyed fresh but can be reheated for a quick meal.

Nutrition & Diet Analysis (per serving)

Each serving of Tuna Cheese Biscuit Casserole contains roughly 551 calories, with 28g protein, 68g carbohydrates, and 19g fat. It is an excellent source of protein (55% of the Daily Value) and iron (28% of the Daily Value), and a good source of potassium. Note that it is relatively high in sodium, at 1043mg per serving (45% of the Daily Value).

551 kcal 28% DV
Protein Fat Carbs

Macronutrients

Protein 27.7g 55% DV
Total Fat 19.4g 25% DV
Carbs 67.6g 25% DV
Fiber 2.2g 8% DV
Sugar 8.6g 17% DV

Electrolytes

Sodium 1042.9mg 45% DV
Potassium 594.7mg 13% DV
Cholesterol 36.5mg 12% DV

Vitamins & Minerals

Vitamin A 31.1mcg 3% DV
Vitamin C 2.8mg 3% DV
Vitamin D 1.3mcg 7% DV
Calcium 89mg 7% DV
Iron 5mg 28% DV
Diet fit High-protein
Contains Milk Fish

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I use fresh tuna instead of canned?

Yes, you can use fresh tuna, but it will require cooking and flaking before adding it to the casserole. Make sure to season it well for the best flavor, as canned tuna is already seasoned.

What can I substitute for the biscuits?

If you don't have refrigerated biscuits, you can use crescent roll dough or make your own biscuit dough from scratch. Alternatively, consider serving the tuna mixture over a bed of cooked rice or pasta for a different twist.

Can I freeze this casserole?

Yes, you can freeze the casserole before baking. Just assemble it in a freezer-safe dish, cover tightly, and freeze for up to 2 months. When ready to bake, thaw it in the refrigerator overnight and then bake as directed.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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