Tuna-Egg-Cheese Overnight Casserole

Prep: 10 min Cook: 75 min Serves: 8 Cuisine: American

A hearty overnight casserole combining tuna, eggs, cheese, and pasta, perfect for a comforting family meal or a make-ahead dish for busy mornings.

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Ingredients

  • 1 3/4 cups uncooked macaroni
  • 2 cups tuna
  • 3 hard-boiled eggs
  • 1/2 pound shredded American or sharp cheese
  • 2 cups milk
  • 2 cans mushroom soup

Instructions

  1. Grease a casserole dish.
  2. Mix all ingredients together in the dish.
  3. Refrigerate overnight.
  4. Bake at 350°F (175°C) for 1 1/4 hours.

Tips & Substitutions

For a creamier texture, consider using half-and-half instead of milk. You can also substitute the tuna with canned chicken or a plant-based protein for a different flavor profile. If you're short on time, pre-cooked macaroni can be used. For added flavor, mix in some herbs or spices, such as dill or paprika, which are common in American recipes.

Serving Suggestions

This casserole is hearty enough to serve as a main dish. Pair it with a fresh green salad or steamed vegetables for a balanced meal. A side of garlic bread complements the flavors well. For a fun twist, serve it alongside Easy Tuna Turnovers for a varied seafood spread.

Storage & Reheating

Store leftovers in an airtight container in the refrigerator for up to three days. To reheat, cover with foil and warm in the oven at 350°F (175°C) for about 20-30 minutes, or until heated through. You can also microwave individual portions, adding a splash of milk to keep it moist.

Nutrition & Diet Analysis (per serving)

Each serving of Tuna-Egg-Cheese Overnight Casserole contains roughly 731 calories, with 26g protein, 117g carbohydrates, and 18g fat. It is an excellent source of protein (52% of the Daily Value), iron (47% of the Daily Value), and calcium (46% of the Daily Value), and a good source of vitamin C and potassium. Note that it is relatively high in sodium, at 1024mg per serving (45% of the Daily Value).

731 kcal 37% DV
Protein Fat Carbs

Macronutrients

Protein 26.2g 52% DV
Total Fat 18g 23% DV
Carbs 116.8g 42% DV
Fiber 1.1g 4% DV
Sugar 47.4g 95% DV

Electrolytes

Sodium 1024.4mg 45% DV
Potassium 641.9mg 14% DV
Cholesterol 132.1mg 44% DV

Vitamins & Minerals

Vitamin A 241.9mcg 27% DV
Vitamin C 16.1mg 18% DV
Vitamin D 2.4mcg 12% DV
Calcium 593mg 46% DV
Iron 8.4mg 47% DV
Diet fit High-protein Low-fat
Contains Milk Egg Fish

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I make this casserole ahead of time?

Yes, this casserole is perfect for making ahead. Simply prepare it the night before, refrigerate, and bake it the next day. This allows the flavors to meld beautifully, making it even tastier.

What can I substitute for the mushroom soup?

If you prefer a different flavor, you can use cream of chicken soup or a homemade white sauce. For a lighter option, you might consider a vegetable broth mixed with a bit of flour for thickness.

Is it possible to freeze this casserole?

Yes, you can freeze the casserole before baking. Wrap it tightly with plastic wrap and aluminum foil. When ready to bake, thaw it overnight in the refrigerator, then bake as directed. It may require a bit longer to heat through.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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