Artichoke Pasta Casserole

Prep: 15 min Cook: 60 min Serves: 6 Cuisine: Mediterranean

A flavorful baked pasta casserole featuring artichokes, salami, fresh vegetables, and cheesy goodness, perfect for family dinners or entertaining guests with bold, savory flavors.

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Ingredients

  • 6 oz. cooked vermicelli
  • 2 sliced carrots
  • 2 sliced zucchini
  • 1/2 cup garlic wine vinegar
  • 2 small jars artichoke hearts
  • 4 oz. grated Parmesan cheese
  • 8 oz. shredded Mozzarella cheese
  • 6 oz. sliced Italian dried salami
  • 1 1/2 tsp. dry mustard
  • 1 tsp. rosemary
  • 1 tsp. pepper
  • 1/4 cup oil

Instructions

  1. Mix garlic wine vinegar, oil, dry mustard, rosemary, and pepper in a bowl.
  2. Add artichoke hearts, sliced salami, sliced carrots, and sliced zucchini to the mixture.
  3. Mix all ingredients well to coat evenly.
  4. Add cooked and drained vermicelli to the mixture and combine thoroughly.
  5. Stir in shredded Mozzarella cheese.
  6. Transfer the mixture to a baking dish and cover with foil.
  7. Bake at 350°F for 45 minutes, then remove foil.
  8. Top with grated Parmesan cheese and bake uncovered for an additional 15 minutes until cheese is bubbly and golden.

Tips & Substitutions

To enhance the flavors, consider marinating the artichoke hearts in garlic wine vinegar a few hours before use. If you want a vegetarian version, substitute salami with chopped mushrooms or olives. You can also use whole wheat vermicelli for a healthier alternative. For a bit more heat, add red pepper flakes to the mixture.

Serving Suggestions

This Artichoke Pasta Casserole pairs beautifully with a mixed green salad and crusty bread for a satisfying meal. For an Italian twist, serve with a side of garlic bread or bruschetta. A light white wine, such as Pinot Grigio, complements the flavors nicely. For a complete Mediterranean experience, consider browsing more Mediterranean recipes.

Storage & Reheating

Store any leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, place the casserole in a preheated oven at 350°F for about 20 minutes, or until heated through. You can also microwave individual portions for a quick meal, but the oven method helps keep the cheese bubbly.

Nutrition & Diet Analysis (per serving)

Each serving of Artichoke Pasta Casserole contains roughly 546 calories, with 13g protein, 43g carbohydrates, and 37g fat. It is an excellent source of vitamin C (43% of the Daily Value), dietary fiber (28% of the Daily Value), and calcium (28% of the Daily Value), and a good source of vitamin A and potassium. Note that it is relatively high in sodium, at 541mg per serving (24% of the Daily Value).

546 kcal 27% DV
Protein Fat Carbs

Macronutrients

Protein 12.7g 25% DV
Total Fat 37.2g 48% DV
Carbs 43.5g 16% DV
Fiber 7.7g 28% DV
Sugar 7.9g 16% DV

Electrolytes

Sodium 540.5mg 24% DV
Potassium 516.9mg 11% DV
Cholesterol 21.9mg 7% DV

Vitamins & Minerals

Vitamin A 140.9mcg 16% DV
Vitamin C 38.7mg 43% DV
Vitamin D 0.2mcg 1% DV
Calcium 359mg 28% DV
Iron 4.7mg 26% DV
Diet fit High-fiber
Contains Milk

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I make this casserole ahead of time?

Yes, you can prepare the casserole up to the baking step a day in advance. Just cover it tightly with foil and refrigerate. When you're ready to bake, allow it to come to room temperature before placing it in the oven to ensure even cooking.

What can I substitute for garlic wine vinegar?

If you don't have garlic wine vinegar, you can use a combination of regular white wine vinegar and minced garlic. Alternatively, lemon juice mixed with a touch of olive oil can provide a similar tangy flavor that works well in this recipe.

Can I freeze the casserole?

Yes, this casserole can be frozen before baking. Assemble the dish, cover it tightly with plastic wrap and then foil, and freeze for up to 2 months. When ready to bake, thaw it in the refrigerator overnight and bake as directed, adding a few extra minutes if needed.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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