Beef Bisquick Bake

Prep: 15 min Cook: 30 min Serves: 8 Cuisine: American

A hearty baked dish combining savory ground beef, vegetables, and cheesy Bisquick topping, perfect for family dinners and comfort food fans seeking a quick, satisfying meal.

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Ingredients

  • 1 lb ground beef
  • 3/4 cup chopped onion
  • 1 cup condensed Cheddar cheese soup
  • 1 cup frozen mixed vegetables
  • 1/4 cup milk
  • 2 cups Bisquick
  • 3/4 cup water
  • 1 cup shredded Cheddar cheese

Instructions

  1. Preheat oven to 400°F.
  2. Grease a baking dish thoroughly.
  3. Cook ground beef and chopped onion in a skillet until beef is browned.
  4. Drain excess grease from the skillet.
  5. Stir in condensed Cheddar cheese soup, frozen mixed vegetables, and milk.
  6. In the baking dish, mix Bisquick and water until just moistened.
  7. Spread the Bisquick mixture evenly in the dish.
  8. Pour the beef mixture over the Bisquick batter.
  9. Sprinkle shredded Cheddar cheese on top.
  10. Bake for 30 minutes until golden and bubbly.

Tips & Substitutions

For a twist, consider adding spices like garlic powder or Italian seasoning to the beef mixture for extra flavor. You can substitute the ground beef with turkey or a plant-based alternative for a lighter option. If you prefer a creamier texture, use cream of mushroom soup instead of Cheddar cheese soup. This dish is a great way to use up leftover veggies from other meals.

Serving Suggestions

This Beef Bisquick Bake pairs beautifully with a simple green salad or steamed broccoli for a complete meal. For a heartier side, consider serving it alongside mashed potatoes or cornbread. It's a versatile dish that can be enjoyed for dinner or as a comforting lunch the next day.

Storage & Reheating

Store any leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, place in the microwave or oven until heated through. If using the oven, cover with foil to prevent drying out. You can also freeze portions for up to 2 months, but the texture may change slightly upon thawing.

Nutrition & Diet Analysis (per serving)

Each serving of Beef Bisquick Bake contains roughly 481 calories, with 14g protein, 55g carbohydrates, and 23g fat. It is an excellent source of calcium (33% of the Daily Value), protein (28% of the Daily Value), and vitamin A (26% of the Daily Value), and a good source of vitamin C. Note that it is relatively high in sodium, at 467mg per serving (20% of the Daily Value).

481 kcal 24% DV
Protein Fat Carbs

Macronutrients

Protein 14.2g 28% DV
Total Fat 22.9g 29% DV
Carbs 54.7g 20% DV
Fiber 1.1g 4% DV
Sugar 29.4g 59% DV

Electrolytes

Sodium 466.7mg 20% DV
Potassium 277.5mg 6% DV
Cholesterol 41.9mg 14% DV

Vitamins & Minerals

Vitamin A 233.3mcg 26% DV
Vitamin C 10mg 11% DV
Vitamin D 1.2mcg 6% DV
Calcium 423.7mg 33% DV
Iron 4.5mg 25% DV
Contains Milk

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I use fresh vegetables instead of frozen?

Yes, you can use fresh vegetables in place of frozen. Just make sure to chop them into small, even pieces and sauté them briefly with the onion and beef to ensure they cook through during baking.

What can I use if I don't have Bisquick?

If you don't have Bisquick, you can make a homemade substitute by mixing 2 cups of all-purpose flour with 1 tablespoon of baking powder and 1/2 teaspoon of salt. This will work just as well in the recipe.

Can I make this dish ahead of time?

Absolutely! You can prepare the beef mixture and Bisquick batter ahead of time and assemble it in the baking dish. Cover and refrigerate it overnight. Just add a few extra minutes to the baking time when you're ready to cook.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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