Beefed-Up Biscuit Casserole

Prep: 15 min Cook: 30 min Serves: 6 Cuisine: American

A hearty casserole combining seasoned ground beef, cheesy biscuits, and creamy sour cream for a flavorful, satisfying meal perfect for family dinners or casual gatherings.

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Ingredients

  • 1 lb ground beef
  • 1/2 cup chopped onion
  • 2 tablespoons instant minced onions
  • 1/4 cup diced green chilies
  • 1/4 cup diced green pepper
  • 1 cup tomato sauce
  • 2 teaspoons chili powder
  • 1/2 teaspoon garlic powder
  • 1 can refrigerated buttermilk or country style biscuits
  • 1 egg

Instructions

  1. Brown ground beef, chopped onion, and green chilies in a skillet; drain excess fat.
  2. Stir in tomato sauce, chili powder, and garlic powder; simmer while preparing the dough.
  3. Separate refrigerated biscuits into 10 layers, pulling each into 2 layers.
  4. Place 10 biscuit layers in an ungreased 8 or 9-inch square baking pan.
  5. Combine 1/2 cup shredded Monterey Jack cheese, sour cream, and a slightly beaten egg in a bowl; mix well.
  6. Remove the meat mixture from heat and stir in the sour cream mixture.
  7. Spoon the meat and sour cream mixture over the biscuit layers in the pan.
  8. Arrange the remaining biscuit layers over the top of the casserole.
  9. Sprinkle the remaining cheese over the top.
  10. Bake at 357°F (around 180°C) for 25 to 30 minutes until golden and bubbly.

Tips & Substitutions

For a flavor boost, consider adding a teaspoon of cumin or smoked paprika to the beef mixture. You can also substitute ground turkey or chicken for a lighter version. If you prefer a spicier casserole, add diced jalapeños or a splash of hot sauce to the meat. Ensure the biscuits are fresh for the best texture.

Serving Suggestions

This casserole pairs beautifully with a simple side salad or steamed vegetables for a balanced meal. Consider serving it with a dollop of sour cream or guacamole on top for added creaminess. It's also delicious alongside cornbread for a comforting dinner experience.

Storage & Reheating

Store leftover casserole in an airtight container in the refrigerator for up to 3 days. To reheat, place it in the microwave or oven until warmed through. If reheating in the oven, cover with foil to prevent the biscuits from drying out while warming.

Nutrition & Diet Analysis (per serving)

Each serving of Beefed-Up Biscuit Casserole contains roughly 424 calories, with 24g protein, 33g carbohydrates, and 23g fat. It is an excellent source of protein (49% of the Daily Value), calcium (45% of the Daily Value), and vitamin A (31% of the Daily Value), and a good source of iron and dietary fiber. Note that it is relatively high in sodium, at 1317mg per serving (57% of the Daily Value).

424 kcal 21% DV
Protein Fat Carbs

Macronutrients

Protein 24.3g 49% DV
Total Fat 23g 30% DV
Carbs 33.4g 12% DV
Fiber 4.6g 17% DV
Sugar 4.5g 9% DV

Electrolytes

Sodium 1316.9mg 57% DV
Potassium 512.3mg 11% DV
Cholesterol 72.1mg 24% DV

Vitamins & Minerals

Vitamin A 279.3mcg 31% DV
Vitamin C 6mg 7% DV
Vitamin D 0.5mcg 3% DV
Calcium 585.1mg 45% DV
Iron 3.3mg 18% DV
Diet fit High-protein
Contains Egg

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I use different types of cheese in this casserole?

Absolutely! Feel free to experiment with cheeses like cheddar, pepper jack, or even a blend for added flavor. Each will bring its unique taste to the dish, enhancing the overall experience.

Is it possible to make this casserole ahead of time?

Yes, you can prepare the meat mixture and layer it with the biscuits in advance. Cover tightly and refrigerate for up to 24 hours. Just bake it when you're ready to serve, adding a few extra minutes to the cooking time if it's cold from the fridge.

Can I freeze the casserole for later use?

Yes, beefed-up biscuit casserole freezes well. Assemble it without baking, cover tightly, and freeze for up to 2 months. When ready to enjoy, thaw overnight in the refrigerator and bake as directed. This is a great option for meal prepping.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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