Creamy Turkey-Mushroom Casserole

Prep: 20 min Cook: 35 min Serves: 6 Cuisine: American

A hearty, creamy casserole combining turkey, mushrooms, bacon, and cheese with a savory biscuit topping, perfect for comforting family dinners or gatherings.

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Ingredients

  • 6 slices bacon
  • 3/4 cup chopped onion
  • 1/2 cup chopped celery
  • 1/4 cup chopped green pepper
  • 1 (4 oz.) can mushroom stems and pieces, drained
  • 2 eggs
  • 1 (10 3/4 oz.) can condensed cream of celery soup
  • 1 cup sour cream
  • 3 cups cooked turkey or chicken, cut-up
  • 1/4 teaspoon salt
  • 1/8 teaspoon pepper
  • 2 cups Bisquick baking mix
  • 1/2 cup shredded Cheddar or American cheese

Instructions

  1. Preheat oven to 350°F.
  2. Grease a 2-quart round casserole dish.
  3. Fry bacon until crisp; remove from skillet and crumble.
  4. Cook and stir onion, celery, green pepper, and mushrooms in bacon fat until tender.
  5. Drain if necessary.
  6. Stir in condensed cream of celery soup, sour cream, cooked turkey or chicken, salt, and pepper; heat until bubbly.
  7. Spread the meat mixture in the prepared casserole.
  8. Mix remaining ingredients (Bisquick baking mix and shredded cheese) just until moistened.
  9. Spread the biscuit topping over the meat mixture.
  10. Bake uncovered until golden brown, about 30 to 35 minutes.

Tips & Substitutions

For a richer flavor, consider adding fresh herbs like thyme or parsley to the meat mixture. If you're short on time, pre-cooked turkey or rotisserie chicken works well as a substitute. You can also swap out the cream of celery soup for cream of mushroom or chicken for a different twist. For a lighter option, use Greek yogurt instead of sour cream.

Serving Suggestions

This creamy casserole pairs beautifully with a fresh green salad or steamed vegetables for a complete meal. Consider serving it alongside crusty bread or a light soup, such as Crab Meat In Shell Soup, for a comforting dinner. It's also great for potlucks or family gatherings, making it a versatile dish.

Storage & Reheating

Store any leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, place the casserole in a preheated oven at 350°F until warmed through, about 20 minutes. You can also microwave individual portions, but be sure to cover them to retain moisture.

Nutrition & Diet Analysis (per serving)

Each serving of Creamy Turkey-Mushroom Casserole contains roughly 226 calories, with 7g protein, 31g carbohydrates, and 9g fat. It is an excellent source of vitamin C (92% of the Daily Value), and a good source of protein and dietary fiber. Note that it is relatively high in sodium, at 1665mg per serving (72% of the Daily Value).

226 kcal 11% DV
Protein Fat Carbs

Macronutrients

Protein 7.3g 15% DV
Total Fat 8.8g 11% DV
Carbs 31.3g 11% DV
Fiber 3g 11% DV
Sugar 4.4g 9% DV

Electrolytes

Sodium 1665.3mg 72% DV
Potassium 495.7mg 11% DV
Cholesterol 56.8mg 19% DV

Vitamins & Minerals

Vitamin A 65mcg 7% DV
Vitamin C 82.7mg 92% DV
Calcium 112.8mg 9% DV
Iron 1.4mg 8% DV
Diet fit Under 400 cal
Contains Milk Egg

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I use different types of cheese in this casserole?

Absolutely! While Cheddar or American cheese is recommended, feel free to experiment with other cheeses like Monterey Jack, Gouda, or even a sprinkle of Parmesan for a unique flavor twist. Just ensure the cheese melts well for that creamy texture.

Can I make this casserole ahead of time?

Yes, you can prepare the casserole in advance. Assemble the dish, cover it tightly, and refrigerate it for up to 24 hours before baking. When ready to serve, just allow it to sit at room temperature for about 30 minutes before baking as directed.

What can I serve on the side with this casserole?

This casserole is hearty on its own, but you can serve it with a simple side of sautéed green beans or a mixed greens salad. For a comforting touch, consider pairing it with some Amazing Rice for a complete meal that balances flavors and textures.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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