Ground Beef-Biscuit Casserole

Prep: 15 min Cook: 25 min Serves: 8 Cuisine: American

A hearty, comforting casserole combining savory ground beef, creamy mushroom sauce, and flaky biscuits, perfect for family dinners and satisfying hunger with rich flavors.

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Ingredients

  • 1 lb ground beef
  • 1 onion
  • 1 can cream of mushroom soup
  • 1 can milk
  • 1 tsp salt
  • 1/4 tsp pepper
  • 1 can refrigerated biscuits

Instructions

  1. Brown ground beef with chopped onion in a skillet, stirring until crumbly; drain excess fat.
  2. Spoon the cooked beef mixture into a 9 x 9-inch baking dish.
  3. In a bowl, mix cream of mushroom soup, milk, salt, and pepper until well combined.
  4. Pour the soup mixture over the ground beef in the baking dish.
  5. Arrange the refrigerated biscuits over the top of the mixture.
  6. Bake at 450°F until the biscuits are golden brown, about 15-20 minutes.

Tips & Substitutions

For added flavor, consider mixing in some garlic powder or Worcestershire sauce with the beef. You can substitute the cream of mushroom soup with cream of chicken soup if preferred. If you're short on time, precooked ground beef works well. For a veggie boost, add frozen mixed vegetables to the beef mixture before baking.

Serving Suggestions

Serve the casserole hot, garnished with chopped parsley for a fresh touch. It pairs wonderfully with a side salad or steamed vegetables for a balanced meal. For a hearty dinner, consider serving with mashed potatoes or alongside the flavorful Easy Beef Bake for variety.

Storage & Reheating

Store leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, place the casserole in the oven at 350°F for about 20 minutes, or until heated through. You can also microwave individual portions, covering them to retain moisture, for about 1-2 minutes.

Nutrition & Diet Analysis (per serving)

Each serving of Ground Beef-Biscuit Casserole contains roughly 295 calories, with 6g protein, 45g carbohydrates, and 11g fat. It is an excellent source of vitamin C (53% of the Daily Value), and a good source of protein and iron. Note that it is relatively high in sodium, at 1404mg per serving (61% of the Daily Value).

295 kcal 15% DV
Protein Fat Carbs

Macronutrients

Protein 6.3g 13% DV
Total Fat 10.8g 14% DV
Carbs 44.7g 16% DV
Fiber 3.1g 11% DV
Sugar 4.2g 8% DV

Electrolytes

Sodium 1404.3mg 61% DV
Potassium 442.5mg 9% DV
Cholesterol 0.3mg

Vitamins & Minerals

Vitamin A 11.8mcg 1% DV
Vitamin C 47.8mg 53% DV
Vitamin D 0mcg
Calcium 37.7mg 3% DV
Iron 2.3mg 13% DV
Diet fit Under 400 cal
Contains Milk

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I make this casserole ahead of time?

Yes, you can prepare the casserole in advance by assembling it and covering it tightly with foil. Store it in the refrigerator and bake it later, adding a few extra minutes to the baking time if it's cold from the fridge.

What can I use instead of refrigerated biscuits?

If you prefer, you can make your own biscuit dough from scratch or use a different type of dough, like crescent roll dough. Just be sure to adjust the baking time as needed to ensure the dough is cooked through.

Is it possible to freeze this casserole?

Absolutely! You can freeze the assembled casserole before baking. Just wrap it tightly with plastic wrap and then foil. When ready to bake, thaw it in the fridge overnight and then bake according to the instructions.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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