Beth'S Favorite Pizza Casserole
A cheesy, flavorful pizza casserole combining pepperoni, mushrooms, and mozzarella for a satisfying family-friendly meal with bold Italian-inspired flavors.
Ingredients
Instructions
- Preheat oven to 350°F (175°C).
- Boil the pepperoni for 5 minutes, then drain and set aside.
- Sauté chopped onion in 2 tablespoons of melted butter for 2 minutes, then set aside.
- Pour the remaining melted butter into an 8-inch baking pan and toss with cooked spaghetti.
- Spread Pizza Quick sauce over the spaghetti.
- Layer cooked pepperoni, sliced mushrooms, grated Swiss cheese, and grated mozzarella cheese on top.
- Sprinkle oregano evenly over the casserole.
- Bake in the preheated oven for about 20 minutes until bubbly and cheese is melted.
Tips & Substitutions
For a twist, substitute the pepperoni with Italian sausage or even veggies for a vegetarian version. If you prefer a crunch, consider adding bell peppers or olives. Use leftover spaghetti or even a different pasta shape if you have it on hand. This dish can also be made ahead of time and refrigerated before baking, making it a great option for busy nights.
Serving Suggestions
Serve this pizza casserole with a fresh side salad or garlic bread for a complete meal. For a fun twist, offer a variety of toppings on the side, allowing guests to customize their servings. This dish pairs beautifully with Paul'S Pasta for a comforting Italian night.
Storage & Reheating
Leftover pizza casserole can be stored in an airtight container in the refrigerator for up to 3 days. To reheat, cover with foil and warm in a preheated oven at 350°F (175°C) for about 15-20 minutes, or until heated through. You can also microwave individual portions for quick reheating.
Nutrition & Diet Analysis (per serving)
Each serving of Beth'S Favorite Pizza Casserole contains roughly 479 calories, with 15g protein, 31g carbohydrates, and 36g fat. It is an excellent source of vitamin D (87% of the Daily Value), calcium (51% of the Daily Value), and iron (50% of the Daily Value), and a good source of potassium and vitamin C. Note that it is relatively high in sodium, at 516mg per serving (22% of the Daily Value).
Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.
* % Daily Values based on a 2,000 calorie diet (FDA 2020).
Frequently Asked Questions
Can I use a different type of cheese?
Absolutely! Feel free to mix and match cheeses based on your preference. Cheddar or provolone can be excellent substitutes for mozzarella or Swiss. Just keep in mind that the flavor and texture may vary slightly depending on the cheese used.
Can I freeze pizza casserole?
Yes, you can freeze pizza casserole before baking. Assemble the dish, cover it tightly with foil or plastic wrap, and freeze for up to 2 months. When ready to bake, thaw in the refrigerator overnight and then bake as directed. It’s perfect for meal prepping!
What can I serve with pizza casserole?
Consider pairing this casserole with a simple arugula salad tossed in a light vinaigrette. You can also serve it with a side of marinara sauce for dipping or some homemade garlic knots for a true Italian feast.
Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).