Cheese-Stuffed Meat Loaf

Prep: 15 min Cook: 60 min Serves: 6 Cuisine: American

Cheese-stuffed meat loaf offers a savory blend of seasoned ground beef and melty cheese, perfect for hearty family dinners or casual gatherings.

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Ingredients

  • 1 1/2 lb. ground beef
  • 1/2 cup chopped onion
  • 1 egg
  • 3/4 cup plain bread crumbs
  • 2 cans (8 oz. each) tomato sauce
  • 1 teaspoon salt
  • dash of pepper
  • 6 slices American cheese, cut in half

Instructions

  1. Preheat oven to 350°F.
  2. Mix ground beef, chopped onion, bread crumbs, salt, pepper, and one can of tomato sauce in a large bowl.
  3. Pat half of the meat mixture into a loaf pan.
  4. Place cheese slices down the center of the meat mixture.
  5. Cover the cheese with the remaining meat mixture, pressing the edges together to seal.
  6. Spread the second can of tomato sauce over the top of the meat loaf.
  7. Bake for 1 hour or until cooked through.

Tips & Substitutions

For added flavor, try mixing in some chopped garlic or Italian herbs into the meat mixture. If you prefer a different cheese, mozzarella or cheddar can work well as substitutes. To ensure a moist meat loaf, avoid overmixing the meat and handle it gently. For a quick twist, you can also incorporate ingredients from American recipes like chopped bell peppers or mushrooms.

Serving Suggestions

This cheese-stuffed meat loaf pairs beautifully with mashed potatoes or a fresh green salad. For a comforting meal, serve it alongside buttered corn or steamed vegetables. You can also slice it for sandwiches the next day, making it a great option for lunch. If you're looking for more hearty options, explore dishes like Souper Meat'N Potatoes Pie.

Storage & Reheating

Store any leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, place slices in the microwave for 1-2 minutes or in the oven at 350°F until warmed through. Consider adding a splash of tomato sauce on top before reheating to keep the meat loaf moist.

Nutrition & Diet Analysis (per serving)

Each serving of Cheese-Stuffed Meat Loaf contains roughly 488 calories, with 10g protein, 66g carbohydrates, and 21g fat. It is an excellent source of vitamin C (32% of the Daily Value) and protein (21% of the Daily Value), and a good source of dietary fiber and iron. Note that it is relatively high in sodium, at 1904mg per serving (83% of the Daily Value).

488 kcal 24% DV
Protein Fat Carbs

Macronutrients

Protein 10.4g 21% DV
Total Fat 21.5g 28% DV
Carbs 65.5g 24% DV
Fiber 4.4g 16% DV
Sugar 8.4g 17% DV

Electrolytes

Sodium 1904.5mg 83% DV
Potassium 445.2mg 9% DV
Cholesterol 55.7mg 19% DV

Vitamins & Minerals

Vitamin A 28.9mcg 3% DV
Vitamin C 28.8mg 32% DV
Vitamin D 0mcg
Calcium 165.4mg 13% DV
Iron 2.5mg 14% DV
Contains Milk Egg Wheat/Gluten

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I use a different type of meat for this recipe?

Yes, you can substitute ground turkey or chicken for a leaner option. Just be aware that the flavor and texture may differ slightly, so consider adding more seasoning or moisture to compensate for the leaner meat.

How do I know when the meat loaf is fully cooked?

The best way to check for doneness is to use a meat thermometer. Insert it into the center of the meat loaf; it should read at least 160°F. If you don’t have a thermometer, ensure the meat is no longer pink inside and the juices run clear.

Can I freeze cheese-stuffed meat loaf?

Absolutely! You can freeze the uncooked meat loaf wrapped tightly in plastic wrap and then foil for up to 3 months. To cook from frozen, bake it at 350°F for about 1.5 hours or until fully cooked. Alternatively, you can freeze leftovers for up to 2 months.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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