Beef-Up Biscuit Casserole

Prep: 15 min Cook: 25 min Serves: 6 Cuisine: American

A hearty casserole combining seasoned ground beef, cheesy biscuits, and creamy sour cream for a satisfying meal perfect for family dinners or casual gatherings.

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Ingredients

  • 1 to 1 1/2 lb. ground beef
  • 1/4 cup diced green peppers or green chiles
  • 2 teaspoons chili powder
  • 1 can biscuits
  • 1/2 cup sour cream
  • 1/2 cup onions
  • 1 can (8 oz.) tomato sauce
  • 1/2 to 3/4 teaspoon garlic salt
  • 1 1/2 cups Cheddar cheese, shredded
  • 1 egg, slightly beaten

Instructions

  1. In a frying pan, brown ground beef, onions, and green peppers. Stir in tomato sauce, chili powder, and garlic salt.
  2. Simmer the meat mixture while preparing the dough.
  3. Separate the biscuits and pull apart into two layers. Press 10 biscuits into the bottom of an ungreased 8 or 9-inch square baking pan.
  4. In a bowl, combine 1/2 cup shredded cheese, sour cream, and the beaten egg. Mix well.
  5. Remove the meat mixture from heat and stir in the sour cream mixture.
  6. Spoon the meat mixture over the biscuit layer in the pan. Arrange the remaining biscuits on top and sprinkle with the remaining cheese.
  7. Bake at 375°F (190°C) for 20 to 30 minutes until golden and bubbly.

Tips & Substitutions

For added flavor, consider sautéing garlic with the onions and green peppers. You can substitute ground turkey or chicken for a leaner option. For a spicier kick, use jalapeños instead of green peppers. If you have leftover biscuits, they can be used up in this dish or served as a side. This recipe is a great way to utilize pantry staples.

Serving Suggestions

This casserole is perfect for a hearty brunch or casual dinner. Serve it with a simple green salad or steamed vegetables for a balanced meal. It pairs beautifully with *Beef With Beans Barbecue* for a satisfying spread. Offering hot sauce or salsa on the side can enhance the flavors for those who enjoy a bit of heat.

Storage & Reheating

Store any leftovers in an airtight container in the refrigerator for up to three days. To reheat, place in a microwave-safe dish and heat in the microwave for 1-2 minutes until warmed through. Alternatively, reheat in the oven at 350°F (175°C) for about 15-20 minutes, covering with foil to prevent drying out.

Nutrition & Diet Analysis (per serving)

Each serving of Beef-Up Biscuit Casserole contains roughly 689 calories, with 32g protein, 51g carbohydrates, and 40g fat. It is an excellent source of protein (65% of the Daily Value), calcium (44% of the Daily Value), and vitamin A (44% of the Daily Value), and a good source of potassium and dietary fiber. Note that it is relatively high in sodium, at 1272mg per serving (55% of the Daily Value).

689 kcal 34% DV
Protein Fat Carbs

Macronutrients

Protein 32.4g 65% DV
Total Fat 40.5g 52% DV
Carbs 51.3g 19% DV
Fiber 3.7g 13% DV
Sugar 1.6g 3% DV

Electrolytes

Sodium 1272mg 55% DV
Potassium 821.3mg 17% DV
Cholesterol 135.9mg 45% DV

Vitamins & Minerals

Vitamin A 396.7mcg 44% DV
Vitamin C 4.8mg 5% DV
Vitamin D 0.5mcg 2% DV
Calcium 574.5mg 44% DV
Iron 5.2mg 29% DV
Diet fit High-protein
Contains Milk Egg

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I make this casserole ahead of time?

Yes, you can prepare the casserole up to the baking step and cover it tightly with plastic wrap. Refrigerate it overnight and bake it fresh the next day. This makes it a great option for meal prep or entertaining guests.

What can I use instead of Cheddar cheese?

You can substitute with Monterey Jack or Pepper Jack cheese for a different flavor profile. Cream cheese can also be mixed in for creaminess. Experiment with different cheeses to find your favorite combination!

Is this dish freezer-friendly?

Absolutely! After baking, let the casserole cool completely, then wrap it tightly in plastic wrap and aluminum foil before freezing. To reheat, simply thaw in the refrigerator overnight and bake until heated through, making it a convenient option for busy nights.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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