Quick Main Dish

Prep: 15 min Cook: 15 min Serves: 4 Cuisine: American

A hearty and flavorful ground beef casserole topped with biscuits, combining savory vegetables and creamy mushroom soup for a quick, satisfying meal perfect for busy weeknights.

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Ingredients

  • 1 lb. ground beef
  • 1/2 c. chopped onions
  • 1/2 c. celery
  • 1/2 c. bell peppers
  • seasoning to taste
  • 1 (1 lb.) can mixed vegetables, drained
  • 1 (10 1/2 oz.) can cream of mushroom soup
  • 1 (4 oz.) can mushrooms

Instructions

  1. Brown the ground beef in a skillet; drain off excess fat.
  2. Add chopped onions, celery, and bell peppers to the meat mixture.
  3. Saute until the vegetables are tender and cooked.
  4. Season the mixture to taste with preferred seasonings.
  5. Stir in drained mixed vegetables, cream of mushroom soup, and sliced mushrooms (if using).
  6. Pour the mixture into a 1 1/2-quart casserole dish.
  7. Place biscuits over the top of the casserole.
  8. Bake at 400°F for 15 minutes or until the biscuits are brown.

Tips & Substitutions

For a quicker preparation, use pre-chopped vegetables or frozen mixed vegetables instead of fresh. You can substitute ground turkey or chicken for a lighter option. If you prefer a creamier texture, add a bit of sour cream or cream cheese to the mixture. Experiment with seasonings like garlic powder or Italian herbs for extra flavor. This dish is reminiscent of classic American recipes, making it a comforting choice.

Serving Suggestions

Serve this hearty casserole with a side salad or crusty bread to balance the richness. Consider pairing it with roasted vegetables or mashed potatoes for a more filling meal. This dish also pairs beautifully with Corned Beef Cabbage Skillet for a delightful dinner spread. For a lighter option, serve it with steamed green beans.

Storage & Reheating

Store leftovers in an airtight container in the refrigerator for up to 3 days. Reheat in the microwave or oven until warmed through, adding a splash of broth or water if it seems dry. For longer storage, freeze the casserole before baking, and it can last up to 3 months in the freezer.

Nutrition & Diet Analysis (per serving)

Each serving of Quick Main Dish contains roughly 468 calories, with 14g protein, 66g carbohydrates, and 17g fat. It is an excellent source of vitamin D (39% of the Daily Value), protein (29% of the Daily Value), and iron (24% of the Daily Value), and a good source of potassium. Note that it is relatively high in sodium, at 977mg per serving (42% of the Daily Value).

468 kcal 23% DV
Protein Fat Carbs

Macronutrients

Protein 14.3g 29% DV
Total Fat 16.9g 22% DV
Carbs 65.8g 24% DV
Fiber 1.4g 5% DV
Sugar 3.1g 6% DV

Electrolytes

Sodium 976.9mg 42% DV
Potassium 819mg 17% DV
Cholesterol 20.4mg 7% DV

Vitamins & Minerals

Vitamin A 18.3mcg 2% DV
Vitamin C 3mg 3% DV
Vitamin D 7.9mcg 39% DV
Calcium 51.6mg 4% DV
Iron 4.3mg 24% DV
Contains Milk

Estimated from ingredients & per-serving nutrition — verify against package labels for allergies or strict diets.

* % Daily Values based on a 2,000 calorie diet (FDA 2020).

Frequently Asked Questions

Can I use different types of meat in this casserole?

Yes, you can substitute ground beef with ground turkey, chicken, or even plant-based meat alternatives for a vegetarian option. Just adjust cooking times as needed to ensure the meat is fully cooked.

What can I use instead of cream of mushroom soup?

If you prefer not to use cream of mushroom soup, you can make a simple white sauce with butter, flour, and milk, or use a homemade mushroom soup recipe. Alternatively, any cream-based soup, like cream of chicken, can also work well.

How do I know when the casserole is done baking?

The casserole is done when the biscuits on top are golden brown and the filling is bubbling around the edges. A toothpick inserted into the biscuit should come out clean. If in doubt, let it bake a few additional minutes to ensure everything is heated through.

Nutrition is estimated from USDA FoodData Central ingredient data and may vary with brand, portion and preparation — see our methodology. This information is for general educational purposes only and is not medical or dietary advice (disclaimer).

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